The Role of the Gut Microbiota in the Prevention and Management of Gestational Diabetes Mellitus: Are We There Yet?

The Journal of Perinatal & Neonatal Nursing
Bernice ManLisa Tussing-Humphreys

Abstract

Current nonpharmacological approaches, including diet and exercise interventions, for preventing and treating gestational diabetes mellitus are effective for less than 50% of women. Recent evidence suggests that the gut microbiome is integrally involved in maternal glucose homeostasis. Changes to the composition and metabolic behavior of the gut microbiota may play a role in the development and persistence of gestational diabetes mellitus. Thus, there is growing interest in targeting the maternal gut microbiome for preventing and managing pregnancy-related diseases including gestational diabetes mellitus. Future progress may come from a systems biology approach to elucidate the role of the gut microbiota in maternal glucose homeostasis.

References

May 9, 2008·The New England Journal of Medicine·UNKNOWN HAPO Study Cooperative Research GroupDavid A Sacks
Nov 20, 2008·The British Journal of Nutrition·Kirsi LaitinenUNKNOWN Nutrition, Allergy, Mucosal Immunology and Intestinal Microbiota Group
Dec 18, 2013·Nature·Lawrence A DavidPeter J Turnbaugh
Jun 4, 2014·Molecular Endocrinology·Gerard ClarkeTimothy G Dinan
Aug 1, 2010·Journal of Developmental Origins of Health and Disease·P M Catalano
Oct 2, 2014·Cell Biochemistry and Biophysics·Penglong ChenYi Wang
Feb 24, 2015·FEMS Microbiology Reviews·Hadar NeumanOmry Koren
Nov 23, 2015·Cell·David ZeeviEran Segal
Aug 9, 2017·MCN. the American Journal of Maternal Child Nursing·Sara M EdwardsElizabeth J Corwin
Oct 6, 2017·Acta Diabetologica·Kati MokkalaKirsi Laitinen
Oct 28, 2017·Acta Obstetricia Et Gynecologica Scandinavica·Sayyid HasanJohan G Eriksson
Nov 14, 2017·Microbes and Environments·Ethan T HillmanCindy H Nakatsu
Jan 26, 2018·Obstetrics and Gynecology·UNKNOWN Committee on Practice Bulletins—Obstetrics
Feb 18, 2018·Current Opinion in Biotechnology·Beatriz Peñalver BernabéJack A Gilbert
Feb 6, 2019·Nutrients·Valentina PonzoSimona Bo
May 31, 2019·Nature·Wenyu ZhouMichael Snyder
Sep 8, 2019·Trends in Microbiology·Shaopu WangCatherine Stanton

❮ Previous
Next ❯

Citations

Feb 3, 2021·The Journal of Perinatal & Neonatal Nursing·Sara Wagner Moyer, Patricia A Kinser
Feb 9, 2021·Frontiers in Medicine·Elisavet StavropoulouEugenia Bezirtzoglou

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.