PMID: 3320555Jan 1, 1987Paper

The role of the hypothalamus in aging of the female reproductive system

Journal of Steroid Biochemistry
P M Wise

Abstract

We have investigated the role of neuroendocrine and neurochemical changes in the age-related deterioration of cyclic female reproductive function. During middle age the timing and amplitude of the proestrous and estradiol-induced LH surge is altered. We have found that the diurnal pattern of norepinephrine turnover is altered in critical hypothalamic areas known to regulate the release of LHRH. These changes may contribute to alterations in the timing and the amplitude of LH release, which may, in turn, affect the ability of rats to maintain regular estrous cycles.

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Citations

Dec 1, 1992·Pharmacology, Biochemistry, and Behavior·P NautonJ Alliot
Aug 1, 1992·Psychoneuroendocrinology·T F Sadow, R T Rubin
Jan 1, 1993·Psychoneuroendocrinology·J AlliotM A Bruhat
Sep 27, 2001·Endocrinology and Metabolism Clinics of North America·J E Hall, S Gill
Oct 1, 1994·Journal of Toxicology and Environmental Health·J T StevensJ C Eldridge
Oct 1, 1994·Journal of Toxicology and Environmental Health·J C EldridgeJ T Stevens
Oct 1, 1994·Journal of Toxicology and Environmental Health·L T WetzelJ C Eldridge
Sep 1, 1996·Environmental Health Perspectives·I H Russo, J Russo
Apr 20, 2007·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Ralph L CooperTammy E Stoker
Aug 1, 2014·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Marilyn Silva, Poorni Iyer
Oct 8, 1997·Journal of Toxicology and Environmental Health·M E AndersenH A Barton
Feb 1, 1995·American Journal of Obstetrics and Gynecology·D W CramerB L Harlow
Mar 9, 2007·Biology of Reproduction·Weiming ZhengLisa M Halvorson
Dec 31, 1997·The American Journal of Physiology·S M PincusW S Evans

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