PMID: 9552361Jan 1, 1995Paper

The role of the Ran GTPase pathway in cell cycle control and interphase nuclear functions

Progress in Cell Cycle Research
M Dasso

Abstract

Ran is a small, highly abundant, nuclear GTPase. Mutants in Ran and in proteins that interact with it disrupt the normal checkpoint control of mitosis with respect to the completion of DNA synthesis. Ran and other components of this pathway are also required for numerous nuclear functions such as RNA export, protein import, RNA processing and DNA replication. It will be important to understand how these facets of Ran's activities are linked and how they promote correct control of the cell cycle. This review examines recent progress in discovering other components of the Ran GTPase pathway and considers how this pathway may be required for the control of the cell cycle.

Citations

Oct 11, 2014·World Journal of Clinical Oncology·Gerardo Daniel Castro, José A Castro
Feb 9, 2002·Teratogenesis, Carcinogenesis, and Mutagenesis·M I Díaz GómezJ A Castro
Apr 15, 1997·Proceedings of the National Academy of Sciences of the United States of America·H SaitohM Dasso
Jan 3, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·J D Moore
Sep 12, 2000·European Journal of Pharmacology·S ValléeS Champion
Jul 31, 1998·American Journal of Human Genetics·M Dasso, R T Pu

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