The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil

Revista Da Sociedade Brasileira De Medicina Tropical
Thania Luiza de Andrade SieiroClemax Couto Sant Anna

Abstract

The teste rápido molecular para tuberculose (TRM-TB) was introduced in 2014 in Brazil for tuberculosis screening. However, its role in adolescents in Brazil has not been studied. A descriptive study of adolescents with suspected tuberculosis using National Laboratory software. Of 852 (15.4%) suspected cases, 131 were positive by TRM-TB and 2% were resistant to rifampicin. Among TRM-TB-positive cases, 105 (91.4%) were culture-positive. Sixty-four of 96 samples were sensitive to rifampicin by TRM-TB; 11 were resistant to other drugs by drug sensitivity test (DST). Among suspected cases, 16% were diagnosed by TRM-TB, of which 17% were drug-resistant by DST.

References

Jul 21, 2015·Infectious Disease Clinics of North America·Silvia S ChiangJeffrey R Starke
Feb 4, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anne F LuetkemeyerUNKNOWN AIDS Clinical Trials Group A5295 and Tuberculosis Trials Consortium Study 34 Teams

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Citations

Aug 28, 2020·The Cochrane Database of Systematic Reviews·Alexander W KayAnna M Mandalakas
Oct 1, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Rafaela Baroni AurilioClemax Couto Sant'Anna
Oct 8, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Rafaela Baroni AurilioClemax Couto Sant'Anna

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