The role of traditional Chinese herbal medicines in cancer therapy--from TCM theory to mechanistic insights

Planta medica
W L Wendy Hsiao, Liang Liu

Abstract

Traditional Chinese medicine-based herbal medicines have gained increasing acceptance worldwide in recent years and are being pursued by pharmaceutical companies as rich resources for drug discovery. For many years, traditional Chinese medicines (TCM) have been applied for the treatment of cancers in China and beyond. Herbal medicines are generally low in cost, plentiful, and show very little toxicity or side effects in clinical practice. However, despite the vast interest and ever-increasing demand, the absence of strong evidence-based research and the lack of standardization of the herbal products are the main obstacles toward the globalization of TCM. In recent years, TCM research has greatly accelerated with the advancement of analytical technologies and methodologies. This review of TCM specifically used in the treatment of cancer is divided into two parts. Part one provides an overview of the philosophy, approaches and progress in TCM-based cancer therapy. Part two summarizes the current understanding of how TCM-derived compounds function as anticancer drugs.

Citations

Apr 25, 2012·Chinese Journal of Integrative Medicine·Xiao-ying Tian, Liang Liu
Jun 15, 2012·Journal of Asian Natural Products Research·Xuan YuanZhi-Ping Wang
Aug 11, 2012·Briefings in Bioinformatics·Elaine L LeungLiang Liu
Dec 17, 2011·Journal of Biomedicine & Biotechnology·Maria P Crespo-Ortiz, Ming Q Wei
Sep 20, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Anna Del PreteCarmelina Loguercio
Jun 7, 2012·Current Oncology·M GrossmanG Batist
Jan 1, 2012·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·Yongli ZhangJiazheng Lu
Nov 30, 2013·TheScientificWorldJournal·Zahra Tayarani-NajaranMahdi Mojarrab
Apr 30, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Chien-Shan ChengJianping Chen
Mar 22, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Dan-Dan ZhaoYan-Long Zhang
May 31, 2014·BioMed Research International·Huajun ChenTong Yu
Jul 31, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Zhiyu WangJiangang Shen
Dec 19, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Jia DuShi-Bing Su
May 15, 2015·Expert Opinion on Therapeutic Patents·Hong Yang, Tonghui Ma
Aug 29, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Chun-Xue YouZhi-Wei Deng
Mar 11, 2016·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Lei BaoYan-Hui Peng
Oct 30, 2014·Chemical Biology & Drug Design·Iten M FawzyKhaled A M Abouzid
Nov 21, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Ziyou WangZunnan Huang
Sep 15, 2015·Complementary Therapies in Medicine·Lun-Chien LoJohn Y Chiang
Jul 3, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Sang-Mi WooSeong-Gyu Ko
Dec 20, 2014·World Journal of Surgical Oncology·Xiaohong LiuXiaodong He
Dec 30, 2014·BMC Complementary and Alternative Medicine·Constant Anatole PiemeAjit Kumar Saxena
Jun 1, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Zhangfeng ZhongYitao Wang
Jan 24, 2012·Journal of Ethnopharmacology·Shengpeng WangYitao Wang
Jul 24, 2013·Journal of Ethnopharmacology·C LauI Meijerman
Feb 6, 2015·Acta Biochimica Et Biophysica Sinica·Bin XuJian Xu

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