The Role of Ultrasound Across the Inflammatory Arthritis Continuum: Focus on "At-Risk" Individuals

Frontiers in Medicine
Laurence DuquennePaul Emery

Abstract

In individuals at-risk of developing inflammatory arthritis, the value of an ultrasound (US) scan assessment to predict progression has been demonstrated repeatedly. However, depending on recruitment criteria, these individuals may be at different stages in the arthritis development continuum, therefore representing a heterogeneous population. As a consequence, the predictive value of ultrasound results may differ between cohorts. As other reviews have focused on the challenges in population recruitment or have combined biomarkers predicting value according to one recruitment pathway, we wanted to focus on the sole use of ultrasound assessment and its variation according to population recruitment criteria. In this review, we discuss the use of ultrasound in the different at-risk populations across the inflammatory arthritis disease continuum. This review demonstrates that although some sub-population data is scarce, ultrasound is best predictive in three at-risk populations: those with a positive ACPA test in the context of non-specific MSK symptoms, those with clinically suspect arthralgia and those with palindromic rheumatism. We consider that ultrasound assessment will be a cornerstone in prediction risk modeling and prevent...Continue Reading

References

Jun 1, 1992·British Journal of Rheumatology·A J SilmanB Ollier
May 14, 2004·Annals of the Rheumatic Diseases·L TerslevH Bliddal
Apr 3, 2008·Arthritis and Rheumatism·Esperanza NaredoUNKNOWN Ultrasound Group of The Spanish Society of Rheumatology
Mar 17, 2009·Joint, Bone, Spine : Revue Du Rhumatisme·Carole RosenbergPierre Bourgeois
Aug 28, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Hsin-Hua ChenDer-Yuan Chen
May 22, 2010·Arthritis Research & Therapy·Lotte A van de StadtDirkjan van Schaardenburg
Feb 3, 2011·The Journal of Rheumatology·Florence MillotUNKNOWN Investigators of the French Early Arthritis Cohort ESPOIR
Nov 1, 2011·Annals of the Rheumatic Diseases·Serena BugattiCarlomaurizio Montecucco
Oct 2, 2014·Arthritis Research & Therapy·Hamed RezaeiRonald F van Vollenhoven
Nov 29, 2015·Annals of the Rheumatic Diseases·Ilaria PadovanoMaria Antonietta D'Agostino
Jan 28, 2016·Arthritis & Rheumatology·Kulveer Mankia, Paul Emery
Dec 20, 2016·Annals of the Rheumatic Diseases·Hanna W van SteenbergenAnnette H M van der Helm-van Mil
Dec 10, 2017·Best Practice & Research. Clinical Rheumatology·Kulveer Mankia, Paul Emery
Jun 26, 2018·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Ying-Hua ZhangXiao-Yan Zhang
Oct 10, 2018·Annals of the Rheumatic Diseases·Kulveer MankiaPaul Emery
Dec 7, 2018·Annals of the Rheumatic Diseases·Danielle M GerlagPaul P Tak
Dec 21, 2018·Arthritis Research & Therapy·Marian H van Beers-TasDirkjan van Schaardenburg

❮ Previous
Next ❯

Methods Mentioned

BETA
imaging techniques

Software Mentioned

OMERACT
EULAR

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.