Dec 17, 2011

The role of vitamin D in the immunopathogenesis of allergic skin diseases

Allergy
A A BensonS P Jariwala

Abstract

Vitamin D plays key roles in innate and adaptive immunity through the stimulation of Toll-like receptors, increasing pro-inflammatory cytokine production, and possibly enhancing T helper type 2 responses. These mechanisms may explain the growing body of evidence connecting vitamin D to allergic diseases, including asthma, food allergies, and allergic rhinitis. The data relating vitamin D to allergic skin diseases are equivocal with studies linking both high and low vitamin D levels to an increased risk of developing atopic dermatitis. In this paper, we describe the role of vitamin D in the immunopathogenesis of atopic dermatitis and other allergic skin diseases.

  • References33
  • Citations48

References

Mentioned in this Paper

Dermatitis, Atopic
Ergocalciferol
Vitamin D
Adaptive Immunity
Vitamin D [EPC]
Henoch-Schoenlein Purpura
Urticaria
D Vitamin
Eczema, Infantile
Allergic Rhinitis (Disorder)

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

The Journal of Allergy and Clinical Immunology
Tissa R HataRichard L Gallo
Immunology and Allergy Clinics of North America
Daniel A Searing, Donald Y M Leung
Annals of Nutrition & Metabolism
Eva S WintergerstDietrich H Hornig
© 2020 Meta ULC. All rights reserved