Dec 17, 2011

The role of vitamin D in the immunopathogenesis of allergic skin diseases

A A BensonS P Jariwala


Vitamin D plays key roles in innate and adaptive immunity through the stimulation of Toll-like receptors, increasing pro-inflammatory cytokine production, and possibly enhancing T helper type 2 responses. These mechanisms may explain the growing body of evidence connecting vitamin D to allergic diseases, including asthma, food allergies, and allergic rhinitis. The data relating vitamin D to allergic skin diseases are equivocal with studies linking both high and low vitamin D levels to an increased risk of developing atopic dermatitis. In this paper, we describe the role of vitamin D in the immunopathogenesis of atopic dermatitis and other allergic skin diseases.

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Mentioned in this Paper

Dermatitis, Atopic
Vitamin D
Adaptive Immunity
Vitamin D [EPC]
Henoch-Schoenlein Purpura
D Vitamin
Eczema, Infantile
Allergic Rhinitis (Disorder)

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