The roles of RFamide-related peptide-3 in mammalian reproductive function and behaviour.

Journal of Neuroendocrinology
Lance J KriegsfeldKazuyoshi Tsutsui

Abstract

To maximise reproductive success, organisms restrict breeding to optimal times of the day or year, when internal physiology and external environmental conditions are suitable for the survival of both parent and offspring. To appropriately coordinate reproductive activity, internal and external standing is communicated to the hypothalamic-pituitary-gonadal axis via a coordinated balance of stimulatory and inhibitory neurochemical systems. The cumulative balance of these mediators ultimately drives the pattern of gonadotrophin-releasing hormone secretion, a neurohormone that stimulates pituitary gonadotrophin secretion. Until 2000, a complementary inhibitor of pituitary gonadotrophin secretion had not been identified. At this time, a novel, avian hypothalamic peptide capable of inhibiting gonadotrophin secretion in cultured quail pituitary cells was uncovered and named gonadotrophin-inhibitory hormone (GnIH). Subsequently, the presence and functional role for the mammalian orthologue of GnIH, RFamide-related peptide, (RFRP-3), was examined, confirming a conserved role for this peptide across several rodent species. To date, a similar distribution and functional role for RFRP-3 have been observed across all mammals investigated, i...Continue Reading

References

Aug 12, 1977·Science·D A Price, M J Greenberg
Mar 1, 1975·Biology of Reproduction·R F Seegal, B D Goldman
Jan 1, 1985·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·T M WongS Y Tse
Feb 1, 1997·Biology of Reproduction·F J KarschS M Moenter
Aug 31, 2000·Biochemical and Biophysical Research Communications·K TsutsuiP J Sharp
Oct 5, 2001·Biochimica Et Biophysica Acta·S FukusumiM Fujino
Feb 13, 2003·Biochimica Et Biophysica Acta·Hiromi YoshidaShuji Hinuma
Apr 25, 2003·Cell and Tissue Research·Kazuyoshi UkenaKazuyoshi Tsutsui
Sep 10, 2003·The Journal of Biological Chemistry·Shoji FukusumiMasahiko Fujino
May 26, 2004·Physiology & Behavior·Jill E Schneider
Feb 15, 2005·Proceedings of the National Academy of Sciences of the United States of America·Takayoshi UbukaKazuyoshi Tsutsui
Feb 8, 2006·Hormones and Behavior·George E BentleyJohn C Wingfield
Feb 10, 2006·Proceedings of the National Academy of Sciences of the United States of America·Lance J KriegsfeldRae Silver
Nov 23, 2007·General and Comparative Endocrinology·George E BentleyKazuyoshi Tsutsui
Dec 15, 2007·Endocrinology·Florent G RevelJens D Mikkelsen
Jul 26, 2008·The Journal of Endocrinology·Masahiro MurakamiKazuyoshi Tsutsui
Apr 14, 2009·Frontiers in Neuroendocrinology·Iain J ClarkeJeremy T Smith
Jun 23, 2009·Proceedings of the National Academy of Sciences of the United States of America·Elizabeth D KirbyDaniela Kaufer
Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Min WuMeenakshi Alreja
Oct 22, 2009·The Journal of Comparative Neurology·Takayoshi UbukaGeorge E Bentley

❮ Previous
Next ❯

Citations

Feb 6, 2013·Progress in Biophysics and Molecular Biology·M J BodenD J Kennaway
Aug 25, 2012·Yi chuan = Hereditas·Wei XiangYing Tan
Nov 30, 2013·Frontiers in Neuroendocrinology·Matthew Bailey, Rae Silver
Jun 13, 2013·General and Comparative Endocrinology·Nerine T JosephRobert P Millar
Mar 7, 2012·General and Comparative Endocrinology·Kazuyoshi TsutsuiLance J Kriegsfeld
Mar 27, 2015·Journal of Medicinal Chemistry·Massimiliano BeltramoVincent Aucagne
Jan 11, 2011·Frontiers in Neuroendocrinology·Iain J Clarke
Jul 26, 2016·Frontiers in Endocrinology·Anna C GeraghtyDaniela Kaufer
Oct 18, 2015·General and Comparative Endocrinology·John C WingfieldK Tsutsui
Apr 23, 2017·Scientific Reports·Mika KiyoharaKazuyoshi Tsutsui
Sep 12, 2017·International Journal of Environmental Research and Public Health·Alberto LeonardiSusanna Esposito
Jul 1, 2017·Journal of Neuroendocrinology·P N SurkinJ Fernández-Solari
Aug 2, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Lori Asarian, Nori Geary
Mar 2, 2016·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·You Lee SonKazuyoshi Tsutsui
Nov 9, 2011·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Takeshi IwasaKazuyoshi Tsutsui
Sep 30, 2015·Endocrinology·Le MinUrsula B Kaiser
Sep 25, 2017·Endocrinology·Kazuyoshi TsutsuiIchiro Miyata
Dec 20, 2015·Hormone Molecular Biology and Clinical Investigation·Onder CelikSudenaz Celik
Jul 1, 2017·Journal of Molecular Neuroscience : MN·Mohammad Saied SalehiMahyar Janahmadi
Apr 27, 2016·The Journal of Comparative Neurology·Rajae TalbiValérie Simonneaux
Dec 7, 2018·Journal of Neuroendocrinology·Emilia GospodarskaJulia Jaroslawska
Dec 9, 2020·Nature Reviews. Endocrinology·David Lopez-RodriguezAnne-Simone Parent
Jan 13, 2011·ACS Medicinal Chemistry Letters·Shinya OishiNobutaka Fujii
Jul 17, 2020·Journal of Medicinal Chemistry·Thuy NguyenYanan Zhang
Nov 11, 2021·Frontiers in Neuroendocrinology·You Lee SonKazuyoshi Tsutsui

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.