The Rome IV versus Rome III criteria for heartburn diagnosis: A comparative study

United European Gastroenterology Journal
Mengyu ZhangYinglian Xiao

Abstract

The phenotypes of heartburn patients are heterogeneous. The objective of this study was to investigate the proportion of heartburn phenotypes in a Chinese population and to compare the Rome IV and III criteria for heartburn diagnosis. A retrospective study was performed among heartburn patients referred for upper endoscopy and esophageal function tests in a tertiary hospital. Their symptoms fulfilled Rome IV and III criteria. A total of 233 patients were included. Fifty-nine patients (25%) were diagnosed with esophagitis, 96 (41%) with non-erosive reflux disease (NERD) and 78 (34%) with functional heartburn (FH) based on Rome III criteria. Approximately 70% of the Rome III NERD patients were changed based on Rome IV criteria, with 36 patients (15%) diagnosed with reflux hypersensitivity (RH) and 32 patients (14%) who didn't fulfill the criteria considered unclassified. The FH and RH patients showed higher esophagogastric junction-contractile integral (EGJ-CI) and less hiatal hernia than did Rome IV NERD patients. The unclassified had more hiatal hernias than the FH and RH (p < 0.05). The EGJ-CI was similar between Rome III NERD and FH cases. The Rome IV criteria were stricter for heartburn diagnosis and superior in distinguishi...Continue Reading

References

Mar 8, 2003·Alimentary Pharmacology & Therapeutics·S D MartinezR Fass
May 9, 2006·Gastroenterology·Jean Paul GalmicheAndre J P M Smout
Jul 20, 2006·The American Journal of Gastroenterology·Frank ZerbibDaniel Sifrim
Aug 25, 2006·The American Journal of Gastroenterology·Nimish VakilUNKNOWN Global Consensus Group
Sep 9, 2008·The American Journal of Gastroenterology·Edoardo SavarinoVincenzo Savarino
Jan 22, 2009·Pain·Charles H Knowles, Qasim Aziz
Nov 4, 2010·Digestive Diseases and Sciences·Vladimir M KushnirC Prakash Gyawali
Mar 8, 2011·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Edoardo SavarinoVincenzo Savarino
Sep 15, 2011·European Journal of Gastroenterology & Hepatology·Paul EnckSibylle Klosterhalfen
Oct 13, 2011·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·M FrazzoniG Melotti
Nov 1, 2011·Journal of Gastroenterology·Edoardo SavarinoVincenzo Savarino
Oct 24, 2012·The American Journal of Gastroenterology·Robert T KavittMichael F Vaezi
Mar 27, 2013·Nature Reviews. Gastroenterology & Hepatology·Edoardo SavarinoVincenzo Savarino
Sep 11, 2013·The American Journal of Gastroenterology·Anisa ShakerC Prakash Gyawali
Oct 24, 2013·World Journal of Gastroenterology : WJG·Michele CicalaMentore Ribolsi
Jan 28, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·F NicodèmeJ E Pandolfino
Jun 12, 2014·United European Gastroenterology Journal·Hidekazu SuzukiToshifumi Hibi
Dec 4, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P J KahrilasUNKNOWN International High Resolution Manometry Working Group
May 5, 2016·Gastroenterology·Qasim AzizFrank Zerbib

❮ Previous
Next ❯

Citations

Aug 14, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Mengyu ZhangYinglian Xiao
Feb 1, 2020·Journal of Gastroenterology and Hepatology·Songfeng ChenYinglian Xiao
Feb 6, 2020·Gastroenterology·Ronnie FassC Prakash Gyawali
Jun 10, 2021·Journal of Digestive Diseases·Ying Lian XiaoUNKNOWN Chinese Society of Gastroenterology
Jul 3, 2021·Journal of Neurogastroenterology and Motility·Songfeng ChenYinglian Xiao

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

Given Imaging
Bravo
SPSS
Manoview
Bioview Analysis

Related Concepts

Related Feeds

Barrett Esophagus

Barrett’s esophagus if a serious complication of gastroesophageal reflux disease during which the normal esophageal lining changes to tissue that resembles intestinal lining. Here is the latest research.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.