PMID: 9442363Jan 27, 1998Paper

The ROMK-cystic fibrosis transmembrane conductance regulator connection: new insights into the relationship between ROMK and cystic fibrosis transmembrane conductance regulator channels

Current Opinion in Nephrology and Hypertension
K Ho

Abstract

The structure of ATP-sensitive K+ (KATP) channels in excitable cells has been elucidated recently. These channels consist of a pore-forming inward rectifier K+ (Kir) channel and four sulfonylurea receptor proteins. In the distal nephron, Kir 1.1 (ROMK) channels probably contribute to the formation of epithelial (KATP) channels. Current findings suggest the possibility that these renal KATP channels consist of Kir 1.1 channel-CFTR complexes and therefore represent structural analogues of classical KATP channels.

References

Jan 1, 1992·Annual Review of Cell Biology·C F Higgins
Apr 24, 1992·Science·N A BradburyK L Kirk
Dec 15, 1992·Biochimica Et Biophysica Acta·S J Ashcroft, F M Ashcroft
Jan 1, 1992·Annual Review of Physiology·W WangG Giebisch
Oct 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·I CrawfordC F Higgins
Jan 1, 1992·Physiological Reviews·F Lang, W Rehwald
Nov 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·W H Wang, G Giebisch
Jan 1, 1990·Cellular Signalling·S J Ashcroft, F M Ashcroft
Apr 20, 1990·Cell·A Ullrich, J Schlessinger
Jan 1, 1990·Pflügers Archiv : European journal of physiology·M BleichR Greger
Aug 1, 1990·The American Journal of Physiology·X Wang, I Kurtz
Jul 1, 1990·Archives of Disease in Childhood·J D KennedyD J Matthew
Jan 1, 1988·Annual Review of Neuroscience·F M Ashcroft
Aug 1, 1989·The Journal of Pediatrics·B StrandvikE Kusoffsky
Aug 4, 1988·The New England Journal of Medicine·S M KatzB Falkner
Jul 1, 1971·The Journal of Pediatrics·A M RobsonS Klahr
Sep 1, 1982·Acta paediatrica Scandinavica·U BergB Strandvik
Mar 1, 1994·Neuron·T BaukrowitzD C Gadsby
Mar 1, 1995·Pflügers Archiv : European journal of physiology·A RabeE Frömter
Aug 11, 1995·Science·M J StuttsR C Boucher
Jun 1, 1995·Current Opinion in Neurobiology·C A DoupnikH A Lester
Jul 7, 1995·The Journal of Biological Chemistry·T TakumiS Nakanishi
Sep 8, 1995·Cell·C F Higgins
Nov 4, 1993·Nature·J A TabcharaniJ W Hanrahan

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Citations

Jun 25, 2004·The Journal of Membrane Biology·H BarrièreP Poujeol
Oct 8, 2008·Pflügers Archiv : European journal of physiology·Wen-Hui Wang, Gerhard Giebisch
Aug 27, 2009·Proceedings of the National Academy of Sciences of the United States of America·Peng YueWen-Hui Wang
Jun 2, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Michael J WatsonRobert Tarran
Jul 6, 2010·Current Opinion in Nephrology and Hypertension·Wen-Hui WangDao-Hong Lin
May 22, 2009·American Journal of Physiology. Renal Physiology·Paul A Welling, Kevin Ho
Dec 25, 2004·Physiological Reviews·Steven C HebertWenhui Wang
Dec 17, 2008·Journal of the American Society of Nephrology : JASN·Peng SunWen-Hui Wang
Apr 18, 2001·The Journal of Physiology·J D KibbleC J Taylor
Dec 17, 2002·The Journal of Biological Chemistry·Yan XuJeffrey A Whitsett
Dec 12, 2002·American Journal of Physiology. Renal Physiology·Radia BelfodilPhilippe Poujeol

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