The root of the phylogenetic tree of human populations

Molecular Biology and Evolution
M Nei, N Takezaki

Abstract

Although African populations have been shown to be most divergent from any other human populations, it has been difficult to establish the root of the phylogenetic tree of human populations since the rate of evolutionary change may vary from population to population owing to the fluctuation of population size and other factors. However, the root can be determined by using the chimpanzee as an outgroup and by employing proper statistical methods. Using this strategy, we constructed phylogenetic trees of human populations for five different sets of gene frequency data. The data sets used were two sets of microsatellite loci data (25 and 8 loci, respectively), restriction fragment length polymorphism (RFLP) data (79 loci), protein polymorphism data (15 loci), and Alu insertion frequency data (4 loci). All these data sets showed that the root is located in the branch connecting African and non-African populations, and in the four data sets the root was established at a significant level. These results indicate that Africans are the first group of people that split from the rest of the human populations.

Citations

Jun 1, 1997·American Journal of Physical Anthropology·M C BortoliniT de A Weimer
May 6, 1999·American Journal of Physical Anthropology·R A KittlesJ C Long
Jun 19, 1998·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·L B JordeA R Rogers
Jul 20, 2010·Interdisciplinary Sciences, Computational Life Sciences·Li ZhuKai Zhang
Feb 20, 1998·Current Opinion in Genetics & Development·A R Templeton
Jan 12, 2005·The American Psychologist·Richard S Cooper
Aug 2, 2013·Journal of Human Genetics·Hao SunZhaoqing Yang
Oct 1, 1996·Nature Genetics·A von HaeselerS Pääbo
Apr 1, 1997·Proceedings of the National Academy of Sciences of the United States of America·L B JordeH C Harpending
Sep 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·J Y ChuL Jin
Sep 3, 2004·Genome Research·David Serre, Svante Pääbo
Jun 11, 2004·Genome Génome / Conseil National De Recherches Canada·F SalaminiJ Wunder
Oct 7, 2003·Annual Review of Genomics and Human Genetics·Rick A Kittles, Kenneth M Weiss
Oct 16, 2004·Annual Review of Genomics and Human Genetics·Guido Barbujani, David B Goldstein
Mar 5, 2016·Scientific Reports·Osamu MatsunariYoshio Yamaoka
Sep 16, 1999·American Journal of Human Genetics·G CooperD C Rubinsztein
Dec 25, 2007·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Qiongying DengXiaoxun Xie
May 20, 2008·Genomics·Austin L HughesMeredith Yeager
Feb 17, 2001·American Journal of Human Genetics·W S WatkinsL B Jorde
Nov 14, 2013·PloS One·Art F Y PoonRichard H Liang
Apr 2, 2003·Annales de génétique·Hassen Chaabani
Aug 4, 2011·International Journal of Evolutionary Biology·Manuella Villar AmadoTomas Hrbek
Mar 17, 2004·Virus Research·Tokio SugiuraHajime Togari
Jun 19, 2007·Genomics, Proteomics & Bioinformatics·Hao Fan, Jia-You Chu
Mar 9, 2002·Molecular Ecology·O UphyrkinaS J O'Brien
Jul 6, 2002·Anais Da Academia Brasileira De Ciências·Francisco M Salzano
Jan 1, 1998·American Journal of Human Biology : the Official Journal of the Human Biology Council·F M SalzanoC E A Coimbra
Apr 18, 2000·Electrophoresis·P WiegandB Brinkmann
Jun 1, 2012·The Journal of Parasitology·Kerry ClarkJoseph Butler
Apr 4, 2013·G3 : Genes - Genomes - Genetics·Trevor J PembertonNoah A Rosenberg
Feb 26, 2000·Journal of Dental Research·E D Shields
Jan 9, 1999·American Journal of Physical Anthropology·M M Lahr, R A Foley

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