[The S3 guideline exocrine pancreatic cancer].

Medizinische Klinik
Thomas Seufferlein, Guido Adler

Abstract

Each year about 13,000 patients are diagnosed with pancreatic cancer in Germany. More than 95% of all pancreatic cancers are ductal adenocarcinomas and originate from malignant transformation of the exocrine pancreas. There is good evidence that ductal pancreatic cancer develops from so-called PanIn lesions of the ductal epithelium (for pancreatic intraepithelial neoplasia). Males and females are affected at a similar rate. In the German cancer registry, ductal pancreatic cancer incidence is ninth in males and seventh in females. Ductal pancreatic cancer is mostly diagnosed at a late stage. This is due to a lack of early symptoms. The tumor is rather refractory to chemo- or radiotherapy. Only R0 resection of the tumor bears a chance of cure. The unfavorable prognosis of ductal pancreatic cancer is reflected by the fact that pancreatic cancer is the fifth leading cause of cancer death and 5-year survival is only 4%. To assess the current evidence in our understanding of carcinogenesis, diagnosis and treatment of pancreatic cancer, the interdiciplinary S3 guideline "Exocrine pancreatic cancer" was established and published in 2007. The aim of this guideline is to improve early diagnosis of pancreatic cancer, to achieve a higher r...Continue Reading

References

Apr 25, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Malcolm J MooreUNKNOWN National Cancer Institute of Canada Clinical Trials Group
Oct 31, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Michael B Farnell
Dec 22, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Claudio BassiHoward A Reber
Mar 21, 2008·Annals of Surgical Oncology·Irene EspositoMarkus W Büchler
Dec 25, 2008·International Journal of Cancer. Journal International Du Cancer·Alina VrielingH Bas Bueno-de-Mesquita
Mar 21, 2009·American Journal of Epidemiology·Li JiaoRachael Z Stolzenberg-Solomon
Apr 29, 2009·Archives of Internal Medicine·Li JiaoRachael Stolzenberg-Solomon
Jun 30, 2009·Journal of the National Cancer Institute·Anne C M ThiébautRachael Z Stolzenberg-Solomon

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Citations

Jul 30, 2010·Der Pathologe·A Tannapfel
Jul 16, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C RouxN Freemantle
Jan 1, 2012·Personalized Medicine·Kathleen Kraft, Wolfgang Hoffmann

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