PMID: 9179054Jun 1, 1997Paper

The safety and efficacy of transcatheter arterial chemoembolization in the treatment of patients with hepatocellular carcinoma and main portal vein obstruction. A prospective controlled study

Cancer
H S LeeC Y Kim

Abstract

Transcatheter arterial chemoembolization (TACE) has been contra-indicated for the treatment of patients with hepatocellular carcinoma (HCC) and main portal vein (MPV) obstruction because of the potential risk of hepatic insufficiency resulting from ischemia after TACE. The current controlled study was undertaken to assess the safety, efficacy, and predictive factors of favorable response to TACE in patients with HCC and MPV obstruction with good hepatic function and adequate collateral circulation around the MPV. Of a total of 47 patients, 31 were treated with TACE, and 16 who declined the procedures were untreated controls. Thirty-six patients (77%) had diffuse-type HCC and 11 (23%) had nodular-type HCC. During the first week after TACE immediate postprocedural complications were evaluated, and the development of hepatic insufficiency as a late complication was assessed at the end of the fourth week. The cumulative survival rate was estimated by the Kaplan-Meier method, and predictors of better prognosis were obtained by univariate and multivariate analyses. Although no patients showed clinical evidence of hepatic insufficiency as an immediate complication, transient fever and abdominal pain were common. Progressive hepatic in...Continue Reading

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Citations

Jan 30, 2015·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Hiroshi YoshidaEiji Uchida
Feb 2, 2013·Journal of Vascular and Interventional Radiology : JVIR·Hyo-Cheol KimJae Hyung Park
Jul 9, 2005·Journal of Vascular and Interventional Radiology : JVIR·David M LiuChing-yee O Wong
Jun 26, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Gino BoilyUNKNOWN Comité de l'évolution des pratiques en oncologie
Jul 2, 2010·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Renumathy DhanasekaranHyun S Kim
May 31, 2011·International Journal of Radiation Oncology, Biology, Physics·Sang Min YoonDong Jin Suh
Jan 18, 2006·Journal of Vascular and Interventional Radiology : JVIR·James M KielyHenry A Pitt
Sep 29, 2009·The Korean Journal of Hepatology·UNKNOWN Korean Liver Cancer Study Group and National Cancer Center, Korea
Apr 7, 2010·The Korean Journal of Hepatology·Il Han Song, Kyung Sik Kim
Jan 9, 2010·International Journal of Radiation Oncology, Biology, Physics·Mercedes IñarrairaeguiBruno Sangro
Feb 17, 2009·Seminars in Oncology Nursing·Carmel SauerlandDavid B Pearlstone
May 28, 2008·Journal of Vascular and Interventional Radiology : JVIR·Mary A MaluccioKaren T Brown
Dec 7, 2007·Journal of Vascular and Interventional Radiology : JVIR·Nishita KotharyJohn H Rundback
Aug 25, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ryo ToyaNatsuo Oya
Mar 17, 2006·Cancer·Maria A Hawkins, Laura A Dawson
Nov 22, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Laura M KulikRiad Salem
Sep 8, 2011·Journal of Surgical Oncology·Bang Wool EomYoung-Woo Kim
Jan 9, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Yang Won MinJoon Hyeok Lee
May 8, 2016·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Umut SarpelEdward Kim
Dec 20, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Ju-Yeon ChoByung Chul Yoo
Feb 28, 2006·Journal of the American College of Surgeons·Iwao IkaiYasuyuki Shimahara
May 9, 2003·Surgical Oncology Clinics of North America·Iwao IkaiYoshio Yamaoka
Dec 3, 2014·Journal of Hepatology·Xavier AdhouteMarc Bourlière
Apr 12, 2016·Journal of Surgical Oncology·Wen-Hui ChanMing-Chin Yu
Jun 30, 2015·Journal of Vascular and Interventional Radiology : JVIR·Sae Rom ChungSang Min Yoon
May 23, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·UNKNOWN Korean Liver Cancer Study Group (KLCSG), UNKNOWN National Cancer Center, Korea (NCC)
Jan 17, 2015·Frontiers in Surgery·Zenichi MoriseMasashi Isetani

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