The safety of low-dose Larrea tridentata (DC) Coville (creosote bush or chaparral): a retrospective clinical study

The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy
S Heron, E Yarnell

Abstract

To determine whether internal use of low doses of Larrea tridentata tincture or topical applications of this traditional herbal medicine are safe. Retrospective review of all people prescribed Larrea for internal or for topical use over a 22-month period. A general naturopathic practice in Sedona, Arizona. Thirteen patients were identified for whom Larrea tincture for internal use was prescribed. An additional 20 female and 3 male patients were identified for whom an extract of Larrea in Ricinus communis (castor) oil for topical use was prescribed. No patient had any history of liver disease. Larrea was prescribed as part of the usual care of each patient. In all cases it was given as either part of a complex herbal formula individualized for each patient containing less than 10% Larrea tincture or as an extract in Ricinus oil for topical use. Serum liver enzyme levels as well as blood urea nitrogen and creatinine levels, glucose levels, electrolytes, bilirubin levels, iron levels, ferritin levels, lipid levels, and complete blood count (CBC) were available for analysis in four patients; general clinical history and physical examination findings were relied on in all other cases. The four patients with complete before and after...Continue Reading

References

Nov 4, 1989·BMJ : British Medical Journal·F B MacGregorP C Hayes
Jan 1, 1995·Proceedings of the Society for Experimental Biology and Medicine·W R ObermeyerS W Page
May 1, 1994·Australian Family Physician·N Abraham
May 1, 1993·Journal of General Internal Medicine·C A Colley, L M Lucas
Mar 20, 1999·The Annals of Pharmacotherapy·B R WilliamsJ Margolies

❮ Previous
Next ❯

Citations

Nov 30, 2002·Toxicon : Official Journal of the International Society on Toxinology·Joshua D LambertRobert T Dorr
Mar 28, 2013·Oxidative Medicine and Cellular Longevity·Silvia Guzmán-BeltránMartha Torres
Aug 16, 2003·Dermatologic Therapy·Josef Smolle
Sep 18, 2010·Phytochemical Analysis : PCA·Patricia W StegeRoberto A Olsina
Jan 23, 2014·Journal of Food Science·Luis Alberto Ortega-RamirezJesus Fernando Ayala-Zavala
Jul 15, 2006·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Saura C SahuMichael W O'Donnell
Jul 8, 2015·Journal of Traditional and Complementary Medicine·John GnabreRu Chih Huang
May 8, 2016·Journal of Ethnopharmacology·Ashutosh SharmaMaría Luisa Villarreal
Mar 4, 2011·Cancer Prevention Research·Chin-Ying ChungGavin P Robertson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.