The SAVI-TF Registry: 1-Year Outcomes of the European Post-Market Registry Using the ACURATE neo Transcatheter Heart Valve Under Real-World Conditions in 1,000 Patients

JACC. Cardiovascular Interventions
Won-Keun KimHelge Möllmann

Abstract

The SAVI-TF (Symetis ACURATE neo Valve Implantation Using Transfemoral Access) registry was initiated to study the ACURATE neo transcatheter heart valve in a large patient population treated under real-world conditions. The self-expanding, supra-annular ACURATE neo prosthesis is a transcatheter heart valve that gained the Conformité Européene mark in 2014, but only limited clinical data are available so far. This prospective, multicenter registry enrolled 1,000 patients at 25 European centers who were followed for 1 year post-procedure. Mean patient age was 81.1 ± 5.2 years; mean logistic European System for Cardiac Operative Risk Evaluation I score, European System for Cardiac Operative Risk Evaluation II score, and Society of Thoracic Surgeons score were 18.1 ± 12.5%, 6.6 ± 7.5%, and 6.0 ± 5.6%, respectively. At 1 year, 8.0% (95% confidence interval [CI]: 6.3% to 9.7%) of patients had died, 2.3% (95% CI: 1.3% to 3.2%) had disabling strokes, and 9.9% (95% CI: 8.1% to 11.8%) had permanent pacemaker implantations. Through 1 year, 5 reinterventions (0.5%; 95% CI: 0.1% to 1.0%) were performed: 3 valve-in-valve and 2 surgical aortic valve replacements. Mean effective orifice area was 1.84 ± 0.43 cm2, mean gradient was 7.3 ± 3.7 mm ...Continue Reading

Citations

Sep 27, 2018·Expert Review of Medical Devices·Tawfiq ChoudhuryRodrigo Bagur
Jan 15, 2019·Current Opinion in Cardiology·Satya ShreenivasGilbert H L Tang
Feb 26, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Costanza PellegriniOliver Husser
Feb 6, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Christos V BourantasPatrick W Serruys
Oct 15, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Janarthanan SathananthanJohn G Webb
Mar 13, 2020·Expert Review of Medical Devices·Alberto Alperi GarciaJosep Rodés-Cabau
May 24, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Dimytri A SiqueiraAlexandre A C Abizaid
Sep 5, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nynke H KooistraPieter R Stella
Aug 10, 2020·Current Cardiology Reports·Taishi OkunoThomas Pilgrim
Nov 28, 2018·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Janarthanan SathananthanJohn G Webb
Jul 5, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Sebastian BarthKarsten Hamm
Dec 15, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Ignacio J Amat-SantosJ Alberto San Roman
Feb 23, 2021·Journal of Cardiac Surgery·Henri BenkemounMarc Beaufigeau
Mar 19, 2021·Future Cardiology·Jan-Erik GuelkerOliver Husser
Jun 21, 2021·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Helge MöllmannWon-Keun Kim
Aug 29, 2020·Journal of the American College of Cardiology·Sung-Han YoonUNKNOWN Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Registry Investigators
Oct 12, 2021·Trends in Cardiovascular Medicine·Zachary TugaoenJohn Vavalle
Jun 18, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mathias WolfrumStefan Toggweiler
Nov 19, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Ashan GunarathneKamran Baig

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