Mar 28, 2014

The Scramble Conversion Tool

BioRxiv : the Preprint Server for Biology
James K Bonfield


Motivation The reference CRAM file format implementation is in Java. We present “Scramble”: a new C implementation of SAM, BAM and CRAM file I/O. Results The C API for CRAM is 1.5–1.7x slower than BAM at decoding, but 1.8–2.6x faster at encoding. We see file size savings of 40–50%. Availability Source code is available from [][1] [1]:

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Mentioned in this Paper

CCRL2 gene
CCRL2 protein, human
DPYSL5 gene
Systolic Anterior Movement of Mitral Valve
c new
Active ingredient

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