May 23, 2009

The second wave of synthetic biology: from modules to systems

Nature Reviews. Molecular Cell Biology
Priscilla E M Purnick, Ron Weiss

Abstract

Synthetic biology is a research field that combines the investigative nature of biology with the constructive nature of engineering. Efforts in synthetic biology have largely focused on the creation and perfection of genetic devices and small modules that are constructed from these devices. But to view cells as true 'programmable' entities, it is now essential to develop effective strategies for assembling devices and modules into intricate, customizable larger scale systems. The ability to create such systems will result in innovative approaches to a wide range of applications, such as bioremediation, sustainable energy production and biomedical therapies.

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References

  • References113
  • Citations402

Mentioned in this Paper

In Silico
Genome
Computer Programs and Programming
Biotechnology
Epigenesis, Genetic
Biomedicine
Nanotechnology
Engineering
Gene Modules

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