PMID: 7010313Jan 24, 1981Paper

The secondary structure of the protein L1 binding region of ribosomal 23S RNA. Homologies with putative secondary structures of the L11 mRNA and of a region of mitochondrial 16S rRNA

Nucleic Acids Research
C BranlantJ P Ebel

Abstract

An heterologous complex was formed between E. coli protein L1 and P. vulgaris 23S RNA. We determined the primary structure of the RNA region which remained associated with protein L1 after RNase digestion of this complex. We also identified the loci of this RNA region which are highly susceptible to T1, S1 and Naja oxiana nuclease digestions respectively. By comparison of these results with those previously obtained with the homologous regions of E. coli and B. stearothermophilus 23S RNAs, we postulate a general structure for the protein L1 binding region of bacterial 23S RNA. Both mouse and human mit 16S rRNAs and Xenopus laevis and Tetrahymena 28S rRNAs contain a sequence similar to the E. coli 23s RNS region preceding the L1 binding site. The region of mit 16S rRNA which follows this sequence has a potential secondary structure bearing common features with the L1-associated region of bacterial 23S rRNA. The 5'-end region of the L11 mRNA also has several sequence potential secondary structures displaying striking homologies with the protein L1 binding region of 23S rRNA and this probably explains how protein L1 functions as a translational repressor. One of the L11 mRNA putative structures bears the features common to both th...Continue Reading

References

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Citations

Apr 1, 1994·Journal of Molecular Evolution·D Liao, P P Dennis
Jan 1, 1984·Molecular & General Genetics : MGG·R TakataK Hori
Nov 1, 1987·Molecular & General Genetics : MGG·K R Kearney, M Nomura
Jan 1, 1984·Molecular & General Genetics : MGG·H J HimmelfarbJ D Friesen
May 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·R L GourseR A Zimmermann
Jul 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·N RobakisH Weissbach
Sep 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·G Baughman, M Nomura
Jun 11, 1982·Nucleic Acids Research·I TootsM Saarma
Feb 10, 1984·Nucleic Acids Research·V L Smith, K Beckingham
Dec 21, 1981·Nucleic Acids Research·G M VeldmanJ P Ebel
May 1, 1982·European Journal of Biochemistry·F Takaiwa, M Sugiura
Jul 1, 1998·Annual Review of Biophysics and Biomolecular Structure·P B Moore
Sep 20, 2005·Genome Biology·Ilka M AxmannWolfgang R Hess
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·M A Huynen, P Bork
Sep 17, 2009·Molecular Systems Biology·Jens GeorgWolfgang R Hess
Dec 7, 2005·Journal of Molecular Biology·Natalia NevskayaStanislav Nikonov
Oct 3, 1985·Biochimica Et Biophysica Acta·H A RauéR J Planta
May 24, 2021·Nucleic Acids Research·Stephanie OerumCarine Tisné
Dec 1, 2004·EcoSal Plus·James Ofengand, Mark Del Campo
Aug 1, 1985·Journal of Bacteriology·R J Siehnel, E A Morgan
Jul 1, 1983·Journal of Bacteriology·L D Schultz, J D Friesen

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