The selenium requirement of the puppy

Journal of Animal Physiology and Animal Nutrition
K J WedekindG F Combs

Abstract

Current selenium (Se) recommendations for the puppy are based on extrapolation from other species (0.11 mg Se/kg diet). The purpose of this study was to experimentally determine the Se requirement in puppies. Thirty beagle puppies (average = 8.8 weeks old) were utilized in a randomized complete block design with age, litter and gender used as blocking criteria. Puppies were fed a low Se (0.04 mg Se/kg diet) torula yeast-based diet for 14 days (pre-test period) after which this same diet was supplemented with five levels of Na2SeO3 for 21 days (experimental period) to construct a response curve (0, 0.13, 0.26, 0.39 or 0.52 mg Se/kg diet). Response variables included Se concentrations and Se-dependent glutathione peroxidase activities (GSHpx) in serum as well as serum total triiodothyronine (TT3), serum total thyroxine (TT4) and serum free T4 (FT4). No significant changes in food intake and body weight gain occurred, and no clinical signs of Se deficiency were observed. A breakpoint for serum GSHpx could not be determined in our study due to analytical difficulties. A broken-line, two-slope response in serum Se occurred with a breakpoint at 0.17 mg Se/kg diet. When Se from the basal diet was added to this estimate, the breakpoint...Continue Reading

Citations

Jul 25, 2007·Biological Trace Element Research·Olusegun Lateef Adebayo, Gbenga Adebola Adenuga
Jan 21, 2016·BMC Veterinary Research·Mariëlle van ZelstGeert P J Janssens
Jul 30, 2008·Journal of Animal Physiology and Animal Nutrition·C Jensen, J Pallauf
Apr 5, 2016·PloS One·Mariëlle van ZelstGeert P J Janssens
Feb 11, 2021·Animals : an Open Access Journal From MDPI·Viola ZentrichováSimona Kovaříková

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