The sensitivity of an immature vestibular system to altered gravity

Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
Martin GabrielE Horn

Abstract

Stimulus deprivation or stimulus augmentation can induce long-lasting modifications to sensory and motor systems. If deprivation is effective only during a limited period of life this phase is called "critical period." A critical period was described for the development of the roll-induced vestibuloocular reflex (rVOR) of Xenopus laevis using spaceflights. Spaceflight durations and basic conditions of Xenopus' development did not make it possible to answer the question whether exposure of the immature vestibular organ to weightlessness affects rVOR development. The embryonic development of Pleurodeles waltl is slow enough to solve this problem because the rVOR cannot be induced before 15 dpf. Stage 20-21 embryos (4 dpf) were exposed to microgravity during a 10-day spaceflight, or to 3g hypergravity following the same time schedule. After termination of altered gravity, the rVOR was recorded twice in most animals. The main observations were as follows: (1) after the first rVOR appearance at stage 37 (16 dpf), both rVOR gain and amplitude increased steadily up to saturation levels of 0.22 and 20°, respectively. (2) Three days after termination of microgravity, flight and ground larvae showed no rVOR; 1 day later, the rVOR could b...Continue Reading

References

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Aug 26, 2011·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Eberhard R Horn, Martin Gabriel

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Citations

Oct 15, 2013·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Eberhard R Horn, Martin Gabriel
Sep 21, 2012·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Cécile Huin-SchohnJean-Pol Frippiat

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