PMID: 6982950Dec 1, 1982Paper

The sensitization of near-ultraviolet radiation killing of mammalian cells by the sunscreen agent para-aminobenzoic acid

The Journal of Investigative Dermatology
P J OsgoodD J Davies

Abstract

The wavelengths of sunlight considered to be responsible for erythema and skin cancer formation are in the range 290-340 nm. Formulated sunscreens usually contain an agent that absorbs in this wavelength region, and one of the most widely used is para-aminobenzoic acid (PABA). Previous work has demonstrated the sensitization by PABA of the lethal and mutagenic effects of near-ultraviolet (UV) radiation in a model bacterial system. Experiments with the mouse lymphoma L5178Y cell line have now demonstrated sensitization by PABA of the lethal effect of near-UV radiation, the extent of which, after correction for absorption of UV radiation by PABA, bears a direct relationship to PABA concentration. The limitations of these results in predicting the response of human skin to the presence of PABA during exposure to UV radiation is emphasized.

Citations

Jun 1, 1983·Photochemistry and Photobiology·I E Kochevar, R W Gange
Mar 9, 2002·Photochemistry and Photobiology·Maria NowakowskaWiktor Tatara
May 9, 2013·Photodermatology, Photoimmunology & Photomedicine·Sai Yee ChuahWei-Sheng Chong
Jan 1, 1990·Archives of Dermatological Research·H Flindt-HansenT E Larsen
May 1, 1992·Photochemistry and Photobiology·A A ShawM D Shetlar
Apr 1, 1983·The Australasian Journal of Dermatology·A Watson
May 1, 1992·Photochemistry and Photobiology·A A ShawM D Shetlar
Feb 5, 2019·Chemical & Pharmaceutical Bulletin·Toshinori SuzukiToshifumi Fujino
Dec 1, 1983·Photochemistry and Photobiology·A W Girotti
Oct 14, 2016·Environmental Science and Pollution Research International·Pingping ZhaiJean-Marc Chovelon
May 5, 2021·The Science of the Total Environment·Megan CarveJeff Shimeta
Oct 12, 2021·Physical Chemistry Chemical Physics : PCCP·Natércia D N RodriguesVasilios G Stavros

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Clinical Endocrinology and Metabolism
L Y MatsuokaM F Holick
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao
B GuoZhu Zhu
International Journal of Radiation Oncology, Biology, Physics
Sandhya XavierPeter C Brooks
© 2021 Meta ULC. All rights reserved