The seroepidemiology of malaria in Middle America. II. Studies on the Pacific coast of Costa Rica.

The American Journal of Tropical Medicine and Hygiene
M WarrenJ C Skinner

Abstract

Serologic studies for malaria using the indirect fluorescent antibody technique suggest that active transmission is either absent or very low in 6 villages on the Pacific side of Costa Rica. Positive titers (1:20 or higher) were seen in the under-15-year age group in three of the study localities, but only 5 such responses were encountered among 249 people examined in this age range. In the adults (15 years and over) from the same 3 villages there were 68 positive titers among 161 examined. There were 43 positive responses in 189 adults from the remaining 3 villages where none of 307 persons under 15 years of age showed a titer of 1:20 or higher to any of the 3 malaria antigens tested (Plasmodium falciparum, P. vivax and P. malariae). These data suggest that the positive responses in the latter villages are more likely to be associated with old or imported cases than with current local transmission. Serologic responses of 1:80 or higher to the P. falciparum antigen suggested the continued presence of this parasite in the population in spite of the paucity of positive blood smears with this species in recent years. Positive titers with the P. malariae antigen suggest that this parasite is probably still present in the area. Such...Continue Reading

Citations

Oct 5, 2018·Journal of Medical Entomology·Luis Mario RomeroLuis Fernando Chaves
Mar 6, 2010·Emerging Infectious Diseases·Teun BousemaChris Drakeley
Apr 29, 2020·Parasitology·Luis Fernando ChavesRodrigo Marín Rodríguez
Jan 1, 1980·Transactions of the Royal Society of Tropical Medicine and Hygiene·V ThomasY P Leng
Jul 29, 2016·PloS One·Paola Andrea Camargo-AyalaManuel Alfonso Patarroyo
Nov 30, 2011·Antimicrobial Agents and Chemotherapy·Nimol KhimDidier Ménard
Dec 19, 2018·Malaria Journal·Rajika L DewasurendraNadira D Karunaweera
Apr 27, 2007·Trends in Parasitology·Ivo MuellerJohn C Reeder

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.