The significance and expectations of HIV cure research among people living with HIV in Australia

PloS One
Jennifer PowerJayne Lucke

Abstract

Most people living with HIV (PLHIV) with reliable access to antiretroviral treatment (ART) have a life expectancy similar to uninfected populations. Despite this, HIV can negatively affect their social and psychological wellbeing. This study aimed to enhance understanding of the expectations PLHIV hold for HIV cure research and the implications this has for HIV cure research trials. We interviewed 20 Australian PLHIV about their expectations for HIV cure research outcomes and the impact a potential cure for HIV may have on their everyday lives. Data were analysed thematically, using both inductive and deductive approaches. The significance of a cure for HIV was expressed by participants as something that would offer relief from their sense of vigilance or uncertainty about their health into the future. A cure was also defined in social terms, as alleviation from worry about potential for onward HIV transmission, concerns for friends and family, and the negative impact of HIV-related stigma. Participants did not consider sustained medication-free viral suppression (or remission) as a cure for HIV because this did not offer certainty in remaining virus free in a way that would alleviate these fears and concerns. A cure was seen a...Continue Reading

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Dec 4, 2020·The Lancet. HIV·Sharon R LewinUNKNOWN Sunnylands 2019 Working Group
Mar 27, 2021·AIDS and Behavior·Jennifer PowerAdam Bourne
Jul 2, 2021·BMC Medical Ethics·Karine DubéJeremy Sugarman

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BETA
biopsies

Software Mentioned

NVivo

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