Sep 1, 1977

The significance of aortoiliac atherosclerosis as assessed by Doppler ultrasound

American Journal of Surgery
K J WaltersI F McNeill


A simple, noninvasive method of assessing atherosclerotic aortoiliac obstruction is described using Doppler ultrasound with a concurrent electrocardiogram. The method is significantly more accurate than clinical examination. The pulse wave velocity profile at the common femoral artery is recorded with a nondirectional Doppler probe. The time delay from the R wave of the concurrent electrocardiogram to the ultrasound waveform peak and to a point half-way up the waveform upslope is measured. By evaluating the mean of ten such measurements at each point and then by taking the ratio of the former to the latter, a Proximal Damping Quotient (PDQ) may be derived. If the PDQ is greater than 1.4, significant proximal obstruction is probable. Conversely, a PDQ of less than 1.4 suggests a functionally clear aortoiliac segment. Any patient with a PDQ of less than 1.3 in whom reconstructive surgery is being correlated may thus be spared an aortogram and the affected limb may be investigated by femoral angiography alone. A low PDQ is supporting evidence of an adequate "run-in" to the distal segment when a distal arterial reconstruction is proposed. Similarly, if a femoro-femoral crossover graft is to be used, then significant aortoiliac athe...Continue Reading

  • References2
  • Citations3


Mentioned in this Paper

Blood Flow Velocity
Tomography, Ultrasonic
Entire Femoral Artery
Regional Blood Flow
Limb Structure
Doppler Studies
Lung Diseases, Obstructive
Doppler Ultrasound (Procedure)

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

IGA Glomerulonephritis

IgA glomerulonephritis is a chronic form of glomerulonephritis characterized by deposits of predominantly Iimmunoglobin A in the mesangial area. Discover the latest research on IgA glomerulonephritis here.

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

LRRK2 & Immunity During Infection

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Meningococcal Myelitis

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Alzheimer's Disease: MS4A

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.