The significance of changing needles when inoculating blood cultures: a meta-analysis

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
S J SpitalnicLeonard A Mermel

Abstract

Several recent studies have concluded that the changing of needles prior to inoculation of blood culture bottles does not reduce the contamination rate, although there is a consistent trend toward a reduction in number of contaminated cultures when the needle is changed prior to inoculation. We performed a meta-analysis of available studies prospectively comparing blood culture contamination rates with and without a needle change prior to inoculation. The overall weighted contamination rate when the needle was changed prior to inoculation was 2.0%, compared to 3.7% when the needle was not changed. Since an increase of approximately $5,000 in costs per patient is associated with a contaminated blood culture, this reduction in contamination rate could save approximately $85,000 for every 1,000 cultures performed. Our meta-analysis demonstrates reduced blood culture contamination when the needle used for phlebotomy is changed prior to inoculation. This should be considered when setting clinical policy regarding the performance of blood cultures.

Citations

Jul 27, 2006·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·K ReinhartK Werdan
Jul 10, 2003·The Journal of Infection·R W WatkinT S J Elliott
Apr 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M P WeinsteinL B Reller
Nov 16, 2004·Critical Care Medicine·Jonathan CohenJames Jorgensen
Oct 17, 2006·Clinical Microbiology Reviews·Keri K Hall, Jason A Lyman
Oct 9, 2003·Journal of Clinical Microbiology·Andreas F Widmer
Jun 7, 2003·Journal of Clinical Microbiology·Melvin P Weinstein
Apr 29, 2014·The Journal of Hospital Infection·S Dawson
May 15, 2012·Diagnostic Microbiology and Infectious Disease·Elise WillemsUNKNOWN Bilulu Study Group
Jul 15, 1998·Mayo Clinic Proceedings·R B Schifman
Apr 19, 2013·Seminars in Dialysis·Alexander J Kallen
Dec 18, 2013·Archives of Disease in Childhood. Education and Practice Edition·Surjo Kiran DeMichael Kelsey
Jul 6, 2019·Frontiers in Medicine·Sien OmbeletLiselotte Hardy
May 16, 2012·British Journal of Hospital Medicine·Susan Dawson
Jul 1, 1997·Clinical Microbiology Reviews·L G ReimerM P Weinstein
May 29, 2021·Pediatric Quality & Safety·Elizabeth AllenAmy K Keir
Oct 4, 2005·Archives of Pathology & Laboratory Medicine·Leonas G BekerisPaul N Valenstein

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Fortschritte der Neurologie-Psychiatrie
Brigitte Wildemann
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
M L Wilson
© 2021 Meta ULC. All rights reserved