PMID: 9537472Apr 16, 1998Paper

The significance of intraluminal prostatic crystalloids in benign needle biopsies

The American Journal of Surgical Pathology
R C AntonT M Wheeler

Abstract

Intraluminal prostatic crystalloids (IPC) are more common in prostate cancer acini than in benign acini. This study was undertaken to evaluate the hypothesis that crystalloids seen in a benign biopsy may indicate an increased risk of a concomitant prostatic carcinoma. A total of 600 patients underwent more than one prostate biopsy. For 394 patients the results of the biopsy were either negative or positive for prostate cancer. After exclusion of patients whose biopsy results were considered negative but coded as high-grade prostatic intraepithelial neoplasia or were suspicious for cancer or whose slides were unavailable for review, 331 patients remained. Biopsy results for these patients were evaluated for the presence of IPC. Also, 18 completely-embedded benign prostates from cystoprostatectomy specimens from patients with bladder cancer were evaluated for the presence of IPC. Seven hundred twenty-five biopsy specimens were reviewed; 51 (7%) contained crystalloids. Thirty-two of 634 (5%) benign biopsy specimens and 19 of 91 (21%) prostatic carcinoma biopsy specimens contained crystalloids. Sixteen of 331 patients (5%) had crystalloids in the initial benign biopsy specimen; 6 patients subsequently were determined to have carcin...Continue Reading

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Jan 1, 1989·The Prostate·M FurusatoF K Mostofi
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Citations

Feb 28, 2007·Prostate Cancer and Prostatic Diseases·R S SvatekE A Benaim
Jan 5, 2000·BJU International·J L BurtonJ B Anderson
Apr 13, 1999·The American Journal of Surgical Pathology·J C Papadimitriou, C B Drachenberg
May 8, 2001·American Journal of Clinical Pathology·P Thorson, P A Humphrey
Sep 24, 1999·The Urologic Clinics of North America·K A Iczkowski, D G Bostwick
Jan 4, 2018·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Cristina Magi-Galluzzi
Aug 23, 2017·Critical Reviews in Clinical Laboratory Sciences·Francesca SanguedolceLuigi Cormio
Jul 13, 2006·Archives of Pathology & Laboratory Medicine·David G Bostwick, Isabelle Meiers
Jan 11, 2001·Archives of Pathology & Laboratory Medicine·R B ShahM B Amin

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