The significant influence of having children on the postoperative prognosis of patients with nonsmall cell lung cancer: A propensity score-matched analysis

Cancer Medicine
Shinkichi TakamoriYoshihiko Maehara

Abstract

The aim of this study was to elucidate the relationship between family-associated factors and the postoperative prognosis in patients with nonsmall cell lung cancer (NSCLC). Additionally, we investigated whether having children was associated with the postoperative maintenance of the nutritional status. We selected 438 NSCLC patients who had undergone curative lung resection between 2004 and 2011 at Kyushu University (Fukuoka, Japan), whose family-associated factors were available. Nutritional indices, including the prognostic nutritional index (PNI), were used to estimate the change in the nutritional status for 1 year after surgery. A propensity score analysis was conducted after adjusting the following variables: sex, age, smoking history, performance status, pathological stage, and histological type. Three hundred patients (68.5%) had both children and partners. Forty-nine patients (11.2%) only had children, and 56 (12.8%) patients only had a partner. Thirty-three patients (7.5%) did not have a partner or children. The overall survival (OS) and disease-free survival (DFS) of the partner-present and partner-absent patients did not differ to a statistically significant extent (P = .862 and P = .712, respectively). However, ch...Continue Reading

References

Jan 1, 1992·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·G A KuneL F Watson
Dec 15, 1990·International Journal of Cancer. Journal International Du Cancer·E Lund
Aug 1, 1996·International Journal of Epidemiology·O Kravdal, S Hansen
Apr 4, 2003·International Journal of Cancer. Journal International Du Cancer·Øystein Kravdal
Nov 15, 2007·American Journal of Epidemiology·Emily Grundy, Øystein Kravdal
Mar 31, 2011·Journal of the National Cancer Institute·Alice ZervoudakisMarc J Gunter
Dec 16, 2011·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Issa J DahabrehJessica K Paulus
Mar 20, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Elaine Y L LeungDonald C McMillan
Apr 9, 2013·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Hermine PoghosyanMary E Cooley
Sep 26, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ayal A AizerPaul L Nguyen
Nov 26, 2013·International Journal of Cancer. Journal International Du Cancer·Linda KachuriShelley A Harris
Jun 4, 2014·CA: a Cancer Journal for Clinicians·Carol E DeSantisAhmedin Jemal
Jul 2, 2015·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Beata ŚwiątkowskaNeonila Szeszenia-Dąbrowska
Jan 9, 2016·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Jul 10, 2016·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Fumihiro ShojiYoshihiko Maehara
Aug 10, 2016·European Journal of Epidemiology·Daniela SchmidMichael F Leitzmann
Oct 8, 2016·American Journal of Surgery·Mariam F EskanderJennifer F Tseng
Mar 16, 2017·Journal of Epidemiology and Community Health·K ModigA Ahlbom

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Citations

Sep 16, 2019·International Journal of Clinical Oncology·Yoshihiko MaeharaMasaki Mori

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