PMID: 8965108Apr 1, 1996Paper

The size of territorial brain infarction on CT relates to the degree of internal carotid artery obstruction

Journal of Neurology
J LodderF Kessels

Abstract

We studied the relationship between infarct size and degree of internal carotid artery stenosis in 227 stroke patients without a source of embolism in the heart, who had a CT-verified territorial brain infarct. We used logistic regression analysis adjusting for differences between groups in co-associated variables such as age, sex, hypertension, diabetes mellitus, and a history of ischaemic heart disease. Ipsilateral carotid stenosis greater than 50% was more strongly associated with large than small infarcts; adjusted odds ration [(a)OR]: 4.56; 95% confidence interval (CI): 1.21-17.2; P = 0.02. For ipsilateral carotid occlusion the association was even stronger--(a)OR: 36.80; 95% CI: 2.54-533; P = 0.007. When large infarcts were compared with infarcts of small and moderate size together the ORs were 2.29, 95% CI 1.14-4.58 and 2.57, 95% CI 1.17-5.67 for carotid stenosis or occlusion, respectively. Our data show a relationship between greater than 50% carotid stenosis or occlusion and large brain infarcts. We suggest that haemodynamic impairment may contribute to infarct size in territorial infarcts of non-cardiac origin.

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Citations

Oct 30, 2004·Computer Methods in Biomechanics and Biomedical Engineering·K T MoorheadT David
Jan 13, 2006·Cerebrovascular Diseases·Louis R CaplanMichael G Hennerici
Apr 8, 2014·Academic Radiology·Koichiro FutatsuyaYukunori Korogi
Dec 17, 2014·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Hubertus MüllerRoman F Sztajzel
Mar 1, 2012·Stroke; a Journal of Cerebral Circulation·Alexander W KeedyMax Wintermark
Feb 24, 2018·Journal of Magnetic Resonance Imaging : JMRI·Satoru IdeYukunori Korogi
Mar 27, 2002·European Journal of Anaesthesiology·W Schummer, C Schummer
Apr 1, 2020·Continuum : Lifelong Learning in Neurology·Gisele S Silva, Raul G Nogueira

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