PMID: 15224643Jul 1, 2004Paper

The smoker's--a hemodynamic reality?

Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
Nuno BettencourtVasc Gama

Abstract

Smoking is a well-known cardiovascular risk factor. Despite this, smokers seem to have a better prognosis after an acute coronary syndrome (ACS). It has been suggested that the thrombogenicity of smoke could explain this phenomenon; by causing occlusions or sub-occlusions in minor coronary lesions and leading to earlier ACS in terms of coronary disease. To compare the clinical and hemodynamic characteristics of patients hospitalized for ACS, according to their smoking status. The population of patients hospitalized for ACS between January 1, 2001 and September 30 2002 was divided into two groups, according to the existence (F) or not (NF) of a history of smoking. We compared clinical and epidemiologic characteristics, ECG presentation, coronary anatomy, peak troponin, mortality rate, duration of hospital stay and ejection fraction at date of discharge. Of the 903 patients hospitalized for ACS, 369--mean age 54 years (24-88), 95% men--had a history of smoking. In the NF group mean age was 69 years (29-93), 51% being women. Hypertension and diabetes were more prevalent in NF (71 vs. 47% and 33 vs. 17%). Dyslipidemia was more frequent in F. Presentation with ST elevation was more common in F (38 vs. 24%) (p < 0.01) and peak tropon...Continue Reading

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