PMID: 15387137Sep 25, 2004Paper

The solid-state radiation chemistry of simple amino acids, revisited

Radiation Research
Einar SagstuenEli O Hole

Abstract

The solid-state radiation-induced free radical formation in simple amino acids like alpha-glycine (gly) and L-alpha-alanine (ala) has been the subject of investigations by EPR spectroscopy since the late 1950s. The EPR spectra from crystals of gly and ala generally are very complex due to the simultaneous trapping of several free radicals regardless of irradiation and observation temperatures. Untangling these complex spectra is necessary for understanding the mechanisms for the solid-state radiation chemistry of amino acids. Recently, radical formation in gly and ala after room-temperature irradiation has been reinvestigated in our laboratories using X-, K- and Q-band EPR and ENDOR spectroscopy, combined with the ENDOR-induced EPR (EIE) techniques as well as single-crystal and powder EPR and ENDOR spectrum simulations. Several new radical products have been detected and characterized, most prominently the gly species H2N - C x H - COOH and the ala species H3+N - C x (CH3) - COO and H2N - C x (CH3) - COOH. A short description of these radicals is given, and an overview of the solid-state radiation chemistry of the simple amino acids is presented, based on a review of the literature combined with these recent experimental results.

References

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Citations

Jun 14, 2005·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·N Maltar-Strmecki, B Rakvin
Jan 13, 2010·Health Physics·Felipe ChenOswaldo Baffa
Jun 25, 2010·Radiation and Environmental Biophysics·Igor Shuryak, David J Brenner
Jun 19, 2010·Physical Chemistry Chemical Physics : PCCP·Ewald PauwelsEinar Sagstuen
Dec 21, 2013·Physical Chemistry Chemical Physics : PCCP·Ewald PauwelsEinar Sagstuen
Jul 6, 2019·Journal of Synchrotron Radiation·David M Close, William A Bernhard
Sep 20, 2011·Physical Chemistry Chemical Physics : PCCP·Ewald PauwelsMichel Waroquier
May 1, 2009·The Journal of Physical Chemistry. a·R G WilksA Moewes
Apr 7, 2010·The Journal of Physical Chemistry. B·Yiying Zhou, William H Nelson
Jun 8, 2021·Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials·Nikita E BogdanovElena V Boldyreva
May 29, 2021·Journal of Photochemistry and Photobiology. B, Biology·Chao YangShengjie Xia
Jan 16, 2018·The Journal of Physical Chemistry. a·Jevgenij KusakovskijHenk Vrielinck
Dec 17, 2014·The Journal of Physical Chemistry. B·Live F ØyenEinar Sagstuen
Aug 27, 2011·The Journal of Physical Chemistry. a·Yiying Zhou, William H Nelson
Aug 23, 2017·The Journal of Physical Chemistry. a·Eirik O JåstadCecilia M Futsaether
Aug 4, 2006·The Journal of Physical Chemistry. a·Kjell Tage ØhmanEinar Sagstuen

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