The spatial properties of L- and M-cone inputs to electroretinograms that reflect different types of post-receptoral processing

PloS One
Mellina M JacobJan Kremers

Abstract

We studied the spatial arrangement of L- and M-cone driven electroretinograms (ERGs) reflecting the activity of magno- and parvocellular pathways. L- and M-cone isolating sine wave stimuli were created with a four primary LED stimulator using triple silent substitution paradigms. Temporal frequencies were 8 and 12 Hz, to reflect cone opponent activity, and 30, 36 and 48 Hz to reflect luminance activity. The responses were measured for full-field stimuli and for different circular and annular stimuli. The ERG data confirm the presence of two different mechanisms at intermediate and high temporal frequencies. The responses measured at high temporal frequencies strongly depended upon spatial stimulus configuration. In the full-field conditions, the L-cone driven responses were substantially larger than the full-field M-cone driven responses and also than the L-cone driven responses with smaller stimuli. The M-cone driven responses at full-field and with 70° diameter stimuli displayed similar amplitudes. The L- and M-cone driven responses measured at 8 and 12 Hz were of similar amplitude and approximately in counter-phase. The amplitudes were constant for most stimulus configurations. The results indicate that, when the ERG reflect...Continue Reading

References

Feb 1, 1992·Optometry and Vision Science : Official Publication of the American Academy of Optometry·J V OdomF C Riemslag
Dec 1, 1984·Journal of the Optical Society of America. A, Optics and Image Science·J Neitz, G H Jacobs
Jan 1, 1982·Vision Research·O Estévez, H Spekreijse
Dec 1, 1996·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·A G ShapiroV C Smith
Nov 19, 1997·Visual Neuroscience·G H Jacobs, J F Deegan
Mar 9, 2000·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·J KremersL T Sharpe
Mar 9, 2000·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·S A HagstromJ Neitz
Mar 9, 2000·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·D H BrainardG H Jacobs
Mar 22, 2002·Progress in Retinal and Eye Research·Ronald S HarwerthLouvenia Carter-Dawson
Nov 27, 2002·Vision Research·Samuel G SolomonBarry B Lee
Nov 3, 2004·Visual Neuroscience·I J MurrayA Schild
Oct 21, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Heidi HoferDavid R Williams
Jan 4, 2008·Investigative Ophthalmology & Visual Science·Shigeki MachidaRonald A Bush
Jul 5, 2008·Visual Neuroscience·I J MurrayN R A Parry
Sep 10, 2009·Investigative Ophthalmology & Visual Science·Jan KremersManoel da Silva Filho
Oct 5, 2010·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·N K ChallaA Panorgias
Feb 15, 2012·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Jan Kremers, Gobinda Pangeni
May 16, 2012·The Journal of Physiology·Neil R A ParryJan Kremers
Apr 4, 2014·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Deepika KommanapalliDeclan J McKeefry
Apr 4, 2014·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Declan McKeefryNeil R A Parry
Apr 4, 2014·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Jan KremersNeil R A Parry

❮ Previous
Next ❯

Citations

Mar 15, 2016·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Tina I TsaiJan Kremers
Apr 1, 2018·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Avinash J AherJan Kremers
Nov 15, 2017·Documenta Ophthalmologica. Advances in Ophthalmology·Avinash J AherJan Kremers
Sep 23, 2016·Documenta Ophthalmologica. Advances in Ophthalmology·Jan Kremers, Deepak Bhatt
Mar 28, 2019·Journal of Vision·Alódia BrasilJan Kremers
May 3, 2019·Investigative Ophthalmology & Visual Science·Enyam Komla A MornyTom H Margrain
Jan 29, 2021·Documenta Ophthalmologica. Advances in Ophthalmology·Kallene Summer VidalJan Kremers
Oct 17, 2020·Documenta Ophthalmologica. Advances in Ophthalmology·Mathias G NittmannRadouil Tzekov
Apr 2, 2021·Experimental Eye Research·Jan KremersLaura J Frishman
Jul 10, 2021·Investigative Ophthalmology & Visual Science·Avinash J AherJan Kremers
Aug 7, 2021·Journal of Vision·Jing Chen, Karl R Gegenfurtner

❮ Previous
Next ❯

Software Mentioned

MATLAB
RETIport

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the Optical Society of America. A, Optics, Image Science, and Vision
Jan Kremers, Gobinda Pangeni
Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
Naveen K ChallaAthanasios Panorgias
Journal of the Optical Society of America. A, Optics, Image Science, and Vision
Deepika KommanapalliDeclan J McKeefry
Investigative Ophthalmology & Visual Science
Mirella Telles Salgueiro BarboniJan Kremers
© 2021 Meta ULC. All rights reserved