The Spectrum of Recovery From Fracture-Induced Vertebral Deformity in Pediatric Leukemia

Pediatric Blood & Cancer
Leo C Dal OstoLeanne M Ward

Abstract

Vertebral fractures (VF) are a frequent complication of acute lymphoblastic leukemia. Some children with VF undergo vertebral body reshaping to the point of complete restoration of normal vertebral dimensions. Others are left with permanent vertebral deformity if the degree of reshaping has been incomplete by the time of final adult height attainment. In this report, we describe three children with painful VF at leukemia diagnosis or during chemotherapy. Each patient highlights different clinical trajectories in their recovery from VF and underscores the need for osteoporosis intervention trials with the goal to prevent permanent vertebral deformity in selected patients.

References

Sep 1, 1993·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H K GenantM C Nevitt
Jan 1, 1997·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H BurgerH A Pols
Nov 24, 2001·Archives of Disease in Childhood·N A PandyaC R Pinkerton
Nov 6, 2002·The Journal of Clinical Investigation·Frank RauchFrancis H Glorieux
Mar 25, 2008·Lancet·Ching-Hon PuiA Thomas Look
Jan 13, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S KerkeniC Roux
Feb 13, 2009·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Jacqueline HaltonUNKNOWN Canadian STOPP Consortium
Jun 27, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nathalie AlosLeanne M Ward
Aug 7, 2012·The Journal of Clinical Endocrinology and Metabolism·Sogol Mostoufi-MoabMary B Leonard
Dec 1, 2012·European Journal of Endocrinology·O MäkitieK Jahnukainen
Jul 15, 2015·The Journal of Clinical Endocrinology and Metabolism·Elizabeth A CummingsUNKNOWN Canadian STOPP Consortium (National Pediatric Bone Health Working Group)

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Citations

Oct 25, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J MaL M Ward
Feb 1, 2018·Endocrine Reviews·Vicente GilsanzClifford J Rosen
May 23, 2018·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Leanne M WardUNKNOWN Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) Consortium
Sep 25, 2018·The Journal of Clinical Endocrinology and Metabolism·Jinhui MaUNKNOWN Canadian STOPP Consortium
Jan 16, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Brian LentleUNKNOWN Vertebral Fracture Research Groups of the CaMos, STOPP, and Rotterdam Studies
Nov 20, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Jinhui MaUNKNOWN the Canadian Steroid-Induced Osteoporosis in the Pediatric Population (STOPP) Consortium
Aug 5, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A M HarrisS C Wong
Nov 6, 2020·The Journal of Clinical Endocrinology and Metabolism·Melissa FiscalettiNathalie Alos
Jan 5, 2021·Frontiers in Endocrinology·Leanne M Ward
Mar 31, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Jinhui MaUNKNOWN Canadian STOPP Consortium
Jul 8, 2021·The Journal of Clinical Endocrinology and Metabolism·Leanne M WardBianca Lang

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