The Spectrum of Small Intestinal Lesions in Patients with Unexplained Iron Deficiency Anemia Detected by Video Capsule Endoscopy

Medicina
Antonella ContaldoMariabeatrice Principi

Abstract

Background and objectives: Video-capsule endoscopy (VCE) has shown a large range (38⁻83%) of diagnostic yield in unexplained iron deficiency anemia (IDA) and obscure-occult bleeding. Therefore, we retrospectively investigated the VCE-detected spectrum and the prevalence of small bowel injuries and associated risk factors in inpatients with both of the above reported conditions. Methods: We selected inpatients with IDA (hemoglobin <12 g/dL in women, <13 g/dL in men) and obscure-occult bleeding. We excluded VCE indications other than IDA. Complete medical histories and laboratory tests were collected. All subjects underwent PillCam SB2/SB3. The VCE feature Lewis score was calculated when appropriate. We used the t-test and Fisher's exact test for continuous and categorical variables, respectively, in univariate analysis. For multivariate analysis, we used binomial logistic regression. Results: We retrieved 109 patients (female:male ratio of 53:56; age 63.4 ± 18.9 years). Eighty patients (73.4%) showed ≥1 small bowel lesions. The Lewis score was calculated in 41 patients: 13 (31.7%) showed a mild (<135) and 28 (68.3%) a moderate-severe (135⁻790 and >790, respectively) score. In univariate analysis, the small bowel transit time (6....Continue Reading

References

Dec 17, 2003·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·B AnnibaleG Delle Fave
Sep 29, 2005·Endoscopy·B S LewisS Friedman
Feb 27, 2007·Clinical Biochemistry·Michele PetruzzelliPiero Portincasa
Oct 25, 2007·Alimentary Pharmacology & Therapeutics·I M GralnekB S Lewis
Dec 12, 2007·World Journal of Gastroenterology : WJG·Emanuele RondonottiRoberto de Franchis
May 9, 2008·Endoscopy·E RondonottiUNKNOWN Iberian Group for Capsule Endoscopy
Jan 6, 2011·Alimentary Pharmacology & Therapeutics·A LanasX Calvet
May 13, 2011·Gut·Andrew F GoddardUNKNOWN British Society of Gastroenterology
Oct 20, 2012·Gastrointestinal Endoscopy·Anastasios KoulaouzidisJohn N Plevris
Nov 28, 2012·European Journal of Gastroenterology & Hepatology·Grainne E HolleranDeirdre A McNamara
Jan 25, 2013·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Tor-Arne HagveMarianne Svendsen
May 31, 2014·Gastroenterology Report·Deepak GunjanDeepak K Bhasin
Jun 16, 2014·Current Opinion in Pharmacology·Rory W BlacklerJohn L Wallace
Dec 3, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Angel LanasLuis A García-Rodríguez
Jan 13, 2015·Journal of Gastroenterology·Stephanie D SyerJohn L Wallace
Mar 21, 2015·Digestion·Koji Takeuchi, Hiroshi Satoh
Aug 26, 2015·The American Journal of Gastroenterology·Lauren B GersonJonathan A Leighton
Feb 24, 2016·Frontiers in Medicine·Reza A HejaziMarc J Zuckerman
Aug 21, 2016·The Medical Clinics of North America·Edgar R Naut
Jan 14, 2017·World Journal of Gastroenterology : WJG·Alberto Lué, Angel Lanas
Mar 16, 2017·Liver International : Official Journal of the International Association for the Study of the Liver·Simona OnaliEmmanuel A Tsochatzis

❮ Previous
Next ❯

Citations

May 14, 2020·Journal of Clinical Medicine·Larisa AnghelCristian Stătescu

❮ Previous
Next ❯

Software Mentioned

SPSS Statistics
Rapid

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.