PMID: 18407180Dec 1, 1993Paper

The SRY gene

Trends in Endocrinology and Metabolism : TEM
J R Hawkins

Abstract

SRY was identified in an attempt to clone the mammalian testisdetermining factor. Evidence in the form of sex-reversing mutations and mouse transgenesis experiments indicates that SRY is the testis-determining factor. The cloning of this gene marks the end of the beginning of our understanding of sex determination. This review covers the structure of the SRY gene and its RNA transcripts, along with evidence equating SRY with the mammalian testis-determining factor, its evolution, and biochemical aspects of the SRY protein.

References

Feb 1, 1992·Human Genetics·J R HawkinsP N Goodfellow
Nov 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·K McElreavyF Flamant
Sep 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·J GubbayR Lovell-Badge
Jul 1, 1992·Genomics·K D McElreaveyM Fellous
May 9, 1991·Nature·P KoopmanR Lovell-Badge
Dec 1, 1989·Trends in Genetics : TIG·N Ellis, P N Goodfellow
Aug 19, 1993·Nature·L S WhitfieldP N Goodfellow
Feb 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·C M HaqqM A Weiss
Feb 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·T ZwingmanA Ao

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Citations

Apr 1, 1995·The Journal of Experimental Zoology·M A Juárez-OropezaE Pedernera
Oct 20, 1994·The New England Journal of Medicine·D D Federman
Nov 8, 2005·Environmental Research·Ieuan A HughesJarmo Jääskeläinen
Feb 19, 2002·Clinical Endocrinology·S Faisal Ahmed, Ieuan A Hughes
Dec 5, 2014·Cambridge Quarterly of Healthcare Ethics : CQ : the International Journal of Healthcare Ethics Committees·Nathan Carlin

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