The Stability of Treatment Preferences Among Patients With Advanced Cancer

Journal of Pain and Symptom Management
Lea J JabbarianHolly G Prigerson

Abstract

Stability of patients' treatment preferences has important implications for decisions about concurrent and future treatment. To examine the stability of treatment preferences and correlates among patients with advanced cancer. In this cohort, 104 patients with metastatic cancer, progression after at least one chemotherapy regimen, and an oncologist-estimated life expectancy of six or fewer months participated in structured interviews after clinical visits in which patients' recent scan results were discussed. Interviews were repeated in three monthly follow-ups. At baseline, patients' age, education, sex, race, marital status, insurance status, and type of cancer were documented. At each assessment, patients reported their treatment preferences (i.e., prioritizing life-prolonging vs. comfort), quality of life, and current health status. At baseline (n = 104), 55 (53%) patients preferred life-prolonging care and 49 (47%) preferred comfort care. Patients were followed up for one (n = 104), two (n = 74), or three months (n = 44). Between baseline and Month 1, 84 patients (81%) had stable preferences. During follow-up, preferences of 71 patients (68%) remained stable (equally divided between a consistent preference for life-prolong...Continue Reading

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Apr 15, 2020·Blood Reviews·Tamryn F GrayAreej El-Jawahri
Jul 24, 2021·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Christopher E KnoepkeLarry A Allen

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