PMID: 9173823Jan 1, 1997Paper

The state of the hypophyseal-adrenal system during surgical correction of heart diseases under conditions of different anesthesia and in distant periods after surgery

Anesteziologiia i reanimatologiia
E E LitasovaE V Uglova

Abstract

Blood plasma levels of 11-HOCS were measured in 278 patients with heart diseases operated on under different anesthesia at various stages of surgical correction of the diseases and during the immediate postoperative period. Blood plasma ACTH levels were measured in 137 patients operated on under deep hypothermal protection and hypothermal perfusion. The most manifest hormonal response was observed during surgery under normothermia, whereas under conditions of hypothermal perfusion the reaction to intervention was the minimal. A total of 141 patients were examined in remote periods after surgery. Blood plasma 11-HOCS levels were normal in patients with good and satisfactory results of surgical treatment and increased for decreased in those with unsatisfactory results.

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