The STREAM Trial (Prostatic Artery Embolization for the Treatment of Benign Prostatic Hyperplasia) 24-Month Clinical and Radiological Outcomes.

Cardiovascular and Interventional Radiology
Charles R TappingPhil Boardman

Abstract

To establish factors predictive of success prior to Prostate Artery Embolization (PAE) with MRI imaging. A prospective cohort study of 50 patients with Benign Prostatic Hyperplasia (BPH) were treated with PAE in a single institution. Patients had moderate to severe symptoms of BPH refractory to medical management for at least 6 months. Patients were imaged with multiparametric MRI imaging pre-PAE and at 3 months, 12 months and 24 months post-PAE. Clinical success was measured with IPSS, IIEF and EQ-5D-5L quality of life questionnaires. The technical success was 48/50 (96%).The mean age of the group was 67 (range 54-83). The mean IPSS score pre-PAE was 21 and at 24 months was 8 (p < 0.001). There was no deterioration in erectile function. The mean volume of the prostate post-PAE was reduced at 3 and 12 months post-PAE but not significantly different at 24 months. This did not correlate with the IPSS score. Patients with median lobe enlargement has similar symptomatic improvement as those without median lobe enlargement. Internally within the prostate patients with adenomatous-dominant BPH initially did better than patients with stromal enlargement; however, at 24 months patients with stromal enlargement of the prostate improved ...Continue Reading

References

Mar 30, 2016·Journal of Vascular and Interventional Radiology : JVIR·João PiscoAntónio G Oliveira
Oct 30, 2016·BJU International·Daniel RukstalisDamien M Bolton
Apr 23, 2017·Journal of Vascular and Interventional Radiology : JVIR·Shivank Bhatia
Feb 28, 2018·Cardiovascular and Interventional Radiology·D MacleanT Bryant
Dec 4, 2019·Cardiovascular and Interventional Radiology·Francois H CornelisFrancisco Cesar Carnevale

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Citations

Jul 15, 2021·AJR. American Journal of Roentgenology·Teresa A DiazMotoyo Yano

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