The STRokE DOC trial technique: 'video clip, drip, and/or ship'

International Journal of Stroke : Official Journal of the International Stroke Society
B C MeyerP D Lyden

Abstract

To describe the clinical trial methods of a site-independent telemedicine system used in stroke. A lack of readily available stroke expertise may partly explain the low rate of rt-PA use in acute stroke. Although telemedicine systems can reliably augment expertise available to rural settings, and may increase rt-PA use, point-to-point systems do require fixed base stations. Site-independent systems may minimize delay. The STRokE DOC trial assesses whether site-independent telemedicine effectively and efficiently brings rt-PA to a remote population. STRokE DOC is a 5-year, 400-participant, noninvasive trial, comparing two consultative techniques at four remote sites. Participants are randomized to acute 'STRokE DOC telemedicine' or 'telephone' consultations. Treatment decision accuracy is adjudicated at two time points, using three levels of data availability and an independent auditor. The primary outcome measure is whether there was a 'correct decision to treat or not to treat using rt-PA' at each of three adjudication levels (primarily at Level #2). Secondary outcomes include the number of thrombolytic recommendations, intracerebral hemorrhage, and 90-day outcomes. Using the STRokE DOC system (or telephone evaluation), medica...Continue Reading

References

Dec 14, 1995·The New England Journal of Medicine·UNKNOWN National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
Mar 1, 1995·The American Journal of Emergency Medicine·L G Yamamoto
Feb 5, 1999·Stroke; a Journal of Cerebral Circulation·S R Levine, M Gorman
Mar 7, 2000·JAMA : the Journal of the American Medical Association·I L KatzanC A Sila
Mar 8, 2003·Stroke; a Journal of Cerebral Circulation·Marian P LaMonteWesley Page
Mar 8, 2003·Stroke; a Journal of Cerebral Circulation·Scott L SillimanJosé G Merino
Sep 23, 2003·Stroke; a Journal of Cerebral Circulation·Sam WangRobert J Adams
Nov 25, 2003·Stroke; a Journal of Cerebral Circulation·Andreas WiborgUNKNOWN Telemedicine in Stroke in Swabia Project
Nov 6, 2004·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Lee H SchwammSteven R Levine
Jun 18, 2005·Stroke; a Journal of Cerebral Circulation·Mark J AlbertsUNKNOWN Brain Attack Coalition
Feb 21, 2006·Lancet Neurology·David C HessRobert J Adams

❮ Previous
Next ❯

Citations

Mar 10, 2012·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Bart M DemaerschalkBrett C Meyer
May 1, 2010·Stroke; a Journal of Cerebral Circulation·Bart M DemaerschalkUNKNOWN STRokE DOC AZ TIME Investigators
Sep 18, 2012·Stroke; a Journal of Cerebral Circulation·Bart M DemaerschalkUNKNOWN Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC) in Arizona—The Initial Mayo Clinic Experience
May 24, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Ilana SpokoynyBrett C Meyer
Feb 19, 2013·The American Journal of Emergency Medicine·Thilo HölscherArne Voie
Aug 14, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Brett C Meyer, Bart M Demaerschalk
Mar 6, 2010·Neurologic Clinics·W David Freeman, Kenneth A Vatz
Jul 1, 2008·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Brett C MeyerJanet D Werner
Aug 20, 2009·International Journal of Stroke : Official Journal of the International Stroke Society·B C Meyer, P D Lyden
Sep 18, 2012·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Jennifer J MajersikPhillip A Scott
Dec 5, 2013·Health Affairs·Ricardo Martinez, Brendan Carr
May 9, 2009·Stroke; a Journal of Cerebral Circulation·Lee H SchwammUNKNOWN Interdisciplinary Council on Peripheral Vascular Disease
May 9, 2009·Stroke; a Journal of Cerebral Circulation·Lee H SchwammUNKNOWN Council on Cardiovascular Radiology and Intervention
Sep 10, 2010·Journal of Medical Systems·Leonardo LezcanoMiguel-Angel Sicilia
Dec 5, 2012·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·Yasuhiro Hasegawa

❮ Previous
Next ❯

Methods Mentioned

BETA
PCA

Software Mentioned

STRokE DOC
SPOTRIAS
STRokE
STRokE DOC system
Windows Media 9
[UNK]

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
B C MeyerJanet D Werner
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
B C MeyerThomas Hemmen
© 2022 Meta ULC. All rights reserved