PMID: 22343719DOI: 10.1038/nsmb.2251Feb 22, 2012Paper
The structural basis of transferrin sequestration by transferrin-binding protein B.
Nature Structural & Molecular Biology
Charles CalmettesTrevor F Moraes
Abstract
Neisseria meningitidis, the causative agent of bacterial meningitis, acquires the essential element iron from the host glycoprotein transferrin during infection through a surface transferrin receptor system composed of proteins TbpA and TbpB. Here we present the crystal structures of TbpB from N. meningitidis in its apo form and in complex with human transferrin. The structure reveals how TbpB sequesters and initiates iron release from human transferrin.
References
Feb 1, 1990·Canadian Journal of Microbiology·A B Schryvers, G C Gonzalez
Sep 1, 1993·Vaccine·B DanveM J Quentin-Millet
Jun 1, 1993·Molecular Microbiology·J AlcantaraA B Schryvers
May 1, 1996·Trends in Microbiology·S D Gray-Owen, A B Schryvers
Mar 7, 1998·Molecular Microbiology·C N CornelissenP F Sparling
Aug 26, 1998·Infection and Immunity·L E MyersS M Loosmore
Sep 30, 1998·Biochemistry·L M SteinleinR A Ikeda
Nov 18, 1998·Microbial Pathogenesis·M D RetzerA B Schryvers
Dec 26, 2001·Acta Crystallographica. Section D, Biological Crystallography·D R HallP F Lindley
May 15, 2002·FEMS Microbiology Letters·Nina BaltesGerald-F Gerlach
Apr 2, 2003·Biochemistry·Peter J HalbrooksAnne B Mason
Oct 19, 2005·Proteins·Hui LiJan H Jensen
Jun 24, 2006·The Journal of Biological Chemistry·Jeremy WallySusan K Buchanan
Sep 1, 2009·Molecular Cell·Trevor F MoraesAnthony B Schryvers
Jul 17, 2010·Molecular Microbiology·Jessmi M L LingAnthony B Schryvers
Aug 17, 2010·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Ashley N SteereAnne B Mason
Feb 8, 2011·The Journal of Biological Chemistry·Charles CalmettesTrevor F Moraes
Apr 14, 2011·The Journal of Biological Chemistry·Leslie P SilvaDavid C Schriemer
May 19, 2011·PLoS Pathogens·Hebert Echenique-RiveraDavide Serruto
Jul 27, 2011·Proceedings of the National Academy of Sciences of the United States of America·Brian E EckenrothAnne B Mason
❮ Previous
Next ❯
Citations
Jul 17, 2012·Nature Reviews. Microbiology·M Indriati Hood, Eric P Skaar
Jul 10, 2013·Infection and Immunity·Karen L OstbergCynthia Nau Cornelissen
May 1, 2012·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Hans J Vogel
Jan 28, 2014·PloS One·Ari MorgenthauAnthony B Schryvers
May 7, 2013·Future Microbiology·Keira Melican, Guillaume Duménil
Nov 26, 2013·Future Microbiology·Ari MorgenthauAnthony B Schryvers
Jul 21, 2014·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Ari MorgenthauAnthony B Schryvers
Jun 13, 2015·International Journal of Molecular Sciences·Enrico MalitoMatthew J Bottomley
Oct 24, 2015·Antonie van Leeuwenhoek·Wanhai QinLiancheng Lei
Dec 17, 2015·Nature Communications·Chi T WongStephen A Hare
Sep 11, 2012·Molecular Microbiology·Nicholas NoinajCynthia Nau Cornelissen
Jul 3, 2013·Microbiology·Odile B HarrisonChristopher D Bayliss
Jun 4, 2015·Proteomics·Fernanda L SirotaFrank Eisenhaber
Jul 14, 2012·The Biochemical Journal·Kornelius Zeth
Mar 1, 2012·The Biochemical Journal·Leslie P SilvaAnthony B Schryvers
Dec 17, 2014·Science·Matthew F Barber, Nels C Elde
Apr 1, 2014·Current Opinion in Structural Biology·Nicholas Noinaj, Susan K Buchanan
Aug 12, 2015·Vaccine·David M CurranAnthony B Schryvers
Jan 28, 2017·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·N OstanA B Schryvers
Feb 6, 2017·Pathogens and Disease·Yogesh HoodaTrevor F Moraes
Mar 4, 2017·PLoS Pathogens·Nicholas K H OstanAnthony B Schryvers
Mar 10, 2017·Critical Reviews in Biochemistry and Molecular Biology·Anastassia K Pogoutse, Trevor F Moraes
Jun 1, 2017·Metallomics : Integrated Biometal Science·Toshiki G Nakashige, Elizabeth M Nolan
Jul 15, 2016·Molecular & Cellular Proteomics : MCP·Vladimir SarpeDavid C Schriemer
Mar 25, 2015·MicrobiologyOpen·Paul AdamiakAnthony B Schryvers
Sep 10, 2015·Infection and Immunity·Devin R CashCynthia Nau Cornelissen
Dec 31, 2014·Infection and Immunity·Rafael FrandolosoAnthony B Schryvers
Jul 4, 2017·Frontiers in Cellular and Infection Microbiology·Jan Tommassen, Jesús Arenas
Oct 23, 2019·Nature Microbiology·Camilla E TrevorMatthew K Higgins
May 6, 2020·Journal of Bacteriology·Anastassia K Pogoutse, Trevor F Moraes
Aug 3, 2012·Metallomics : Integrated Biometal Science·Tengfei Zheng, Elizabeth M Nolan
Oct 8, 2014·Acta Crystallographica. Section F, Structural Biology Communications·Cory L BrooksM Joanne Lemieux
May 11, 2018·Scientific Reports·João Antônio GuizzoAnthony Bernard Schryvers
Mar 7, 2019·Frontiers in Immunology·Jamie E FeganAnthony B Schryvers
Mar 3, 2020·Frontiers in Immunology·Maryam Mobarak QamsariAnthony B Schryvers
May 11, 2017·Essays in Biochemistry·Wilma NeumannElizabeth M Nolan
Jun 18, 2017·Frontiers in Cellular and Infection Microbiology·Yogesh HoodaTrevor F Moraes
Oct 24, 2020·Expert Review of Anti-infective Therapy·Lara Valente de SouzaGünter Weiss
Dec 6, 2020·The Journal of Biological Chemistry·Gregory B ColeTrevor F Moraes
Mar 17, 2021·Journal of Immunological Methods·Jamie E FeganAnthony B Schryvers
May 27, 2016·Microbiology Spectrum·Jessica R SheldonDavid E Heinrichs
Nov 6, 2012·Biochemistry·Daniele VeggiMaria Scarselli
Dec 26, 2018·Journal of Proteome Research·Daniel S ZiemianowiczDavid C Schriemer
Nov 3, 2021·Journal of Biomolecular Structure & Dynamics·Abhijeet KaraleAsha Mallya
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Methods Mentioned
BETA
X-ray
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