PMID: 1322748Jun 1, 1992Paper

The structure and function of Na+ channels

Current Opinion in Neurobiology
W Stühmer, A B Parekh


The past year has seen major advances in our understanding of voltage-gated ion channels through a powerful combination of patch-clamp and molecular biological techniques. These approaches have identified regions (in some cases single amino acid residues) that are essential for voltage-dependent activation and inactivation, lining of the pore, and regulation of channel function.


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