PMID: 3320537Jan 1, 1987Paper

The structure and function of progesterone receptors in breast cancer

Journal of Steroid Biochemistry
K B Horwitz

Abstract

This paper is a review of the clinical role of progesterone receptors (PR) in the management of breast cancer, and the use of synthetic progestins in treatment of the metastatic disease. Also reviewed are our basic molecular studies dealing with the structure of human breast cancer PR, focusing on the two hormone binding proteins (the A- and B-receptors) and the role of phosphorylation. A model for the structure of PR and their subcellular compartmentalization following hormone treatment is presented.

References

Jan 1, 1978·Acta Radiologica: Oncology, Radiation, Physics, Biology·W Mattsson
Apr 1, 1975·Steroids·K B Horwitz, W L McGuire
Jan 1, 1979·Cancer Chemotherapy and Pharmacology·M De LenaG Bonadonna
Jul 1, 1976·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R D RubensJ L Hayward
Aug 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·J M JeltschP Chambon
Aug 15, 1986·Science·O M ConneelyB W O'Malley
Oct 1, 1986·Endocrinology·W P SullivanD O Toft
Aug 30, 1985·Biochemical and Biophysical Research Communications·J W Pike, N M Sleator
Feb 1, 1985·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·E J GregoryC H Mims
May 22, 1971·Lancet·V JonesA P Forrest
Feb 1, 1968·Annals of Internal Medicine·F M MuggiaG A Hyman
Aug 5, 1967·British Medical Journal·B A Stoll
Jan 1, 1984·Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer·M De LenaG Di Fronzo
Oct 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·A MigliaccioF Auricchio
Jun 1, 1984·Australian and New Zealand Journal of Medicine·D HedleyR Fox
Nov 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·F LogeatE Milgrom
Jun 1, 1984·The Australian and New Zealand Journal of Surgery·R M BryanF J Morgan
Dec 1, 1983·The New England Journal of Medicine·G M ClarkJ S Marshall
Jan 1, 1983·Breast Cancer Research and Treatment·S SaezB Asselain
Mar 15, 1984·Biochemical and Biophysical Research Communications·R N Kurl, S T Jacob
Sep 1, 1982·European Journal of Cancer & Clinical Oncology·B ClavelE Milgrom
Dec 1, 1981·European Journal of Cancer & Clinical Oncology·I M Holdaway, S J Skinner
Jan 1, 1980·Journal of Cancer Research and Clinical Oncology·K von MaillotW Gunselmann
May 1, 1980·Journal of Steroid Biochemistry·Y NomuraK Matsumoto

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Citations

Jan 1, 1990·The International Journal of Biochemistry·S Barker, G P Vinson
Apr 1, 1996·The Journal of Steroid Biochemistry and Molecular Biology·E Müller-HolznerG Daxenbichler
Jan 1, 1990·Annals of the New York Academy of Sciences·F LabrieY Mérand
Feb 22, 2012·Endocrine-related Cancer·Claudia LanariAlfredo A Molinolo
May 15, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Susana CunhaMaria Cristina Oliveira
Dec 22, 2009·Chemical Communications : Chem Comm·Vanesa Fernández-MoreiraMichael P Coogan
Dec 2, 2008·The Breast : Official Journal of the European Society of Mastology·Rosilene Lima PinheiroLucia Costa-Paiva
Sep 1, 2013·Expert Review of Endocrinology & Metabolism·Jerome H Check, Rachael Cohen
Jan 1, 1991·Annals of the New York Academy of Sciences·J P Landers, T C Spelsberg
Dec 11, 2007·Inorganic Chemistry·Kenneth Kam-Wing LoShuk-Han Cheng
Mar 11, 1992·Critical Reviews in Oncology/hematology·D N Danforth

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