The structure of alpha-helical coiled coils

doi:10.1016/s0065-3233(05)70003-6

PMID: 15837513DOI: 10.1016/s0065-3233(05)70003-6Apr 20, 2005Paper

The structure of alpha-helical coiled coils

Advances in Protein Chemistry

Andrei N Lupas, Markus Gruber

Abstract

alpha-Helical coiled coils are versatile protein domains, supporting a wide range of biological functions. Their fold is probably better understood than that of any other protein; indeed, uniquely among folds, their structure can be computed from a set of parametric equations. Here, we review the principles of coiled-coil structure, the determinants of their folding and stability, and the diversity of structural forms they assume.

Citations

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Sep 27, 2012·Archives of Virology·Xiaodong ShenFuquan Hu

Foldamers with heterogeneous backbones.

Jul 2, 2008·Accounts of Chemical Research·W Seth Horne, Samuel H Gellman

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The native GCN4 leucine-zipper domain does not uniquely specify a dimeric oligomerization state

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The d'--d--d' vertical triad is less discriminating than the a'--a--a' vertical triad in the antiparallel coiled-coil dimer motif.

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Sep 15, 2012·Journal of the American Chemical Society·Jay D SteinkrugerSamuel H Gellman

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Jul 8, 2009·Journal of the American Chemical Society·Michael W GiulianoSamuel H Gellman

Heterotrimeric coiled coils with core residue urea side chains.

Nov 27, 2008·The Journal of Organic Chemistry·Maria L Diss, Alan J Kennan

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Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jun YangJun Qin

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The structure of alpha-helical coiled coils

Abstract

Citations

Functional identification of the DNA packaging terminase from Pseudomonas aeruginosa phage PaP3.

Foldamers with heterogeneous backbones.

Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST

Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation.

The native GCN4 leucine-zipper domain does not uniquely specify a dimeric oligomerization state

The structure of a soluble chemoreceptor suggests a mechanism for propagating conformational signals.

The d'--d--d' vertical triad is less discriminating than the a'--a--a' vertical triad in the antiparallel coiled-coil dimer motif.

Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils.

An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure.

Heterotrimeric coiled coils with core residue urea side chains.

Distinctive circular dichroism signature for 14-helix-bundle formation by beta-peptides.

Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions

Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome.

Design of protein-interaction specificity gives selective bZIP-binding peptides.

A de novo peptide hexamer with a mutable channel.

Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels.

Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly.

A coiled-coil motif that sequesters ions to the hydrophobic core.

Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.

Conserved mechanism for sensor phosphatase control of two-component signaling revealed in the nitrate sensor NarX

Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation.

Coiled-coil protein Scy is a key component of a multiprotein assembly controlling polarized growth in Streptomyces

Dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy.

Designed coiled coils promote folding of a recombinant bacterial collagen.

The S-helix determines the signal in a Tsr receptor/adenylyl cyclase reporter.

Crystal structure of the N-terminal domain of the yeast general corepressor Tup1p and its functional implications.

Anti-antimicrobial peptides: folding-mediated host defense antagonists.

Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis.

Coiled-coil networking shapes cell molecular machinery.

Domain annotation of trimeric autotransporter adhesins--daTAA.

An integrative approach for predicting interactions of protein regions

CCHMM_PROF: a HMM-based coiled-coil predictor with evolutionary information

SCORER 2.0: an algorithm for distinguishing parallel dimeric and trimeric coiled-coil sequences

LOGICOIL--multi-state prediction of coiled-coil oligomeric state

Understanding phototropism: from Darwin to today

CC+: a relational database of coiled-coil structures.

Delineation of structural domains and identification of functionally important residues in DNA repair enzyme exonuclease VII.

Geometric principles in the assembly of α-helical bundles

Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF

Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein

Self-assembling cages from coiled-coil peptide modules

Functional mapping of YadA- and Ail-mediated binding of human factor H to Yersinia enterocolitica serotype O:3.

Identification of critical host mitochondrion-associated genes during Ehrlichia chaffeensis infections.

Tricomponent immunopotentiating system as a novel molecular design strategy for malaria vaccine development

The S helix mediates signal transmission as a HAMP domain coiled-coil extension in the NarX nitrate sensor from Escherichia coli K-12.

Two surfaces of a conserved interdomain linker differentially affect output from the RST sensing module of the Bacillus subtilis stressosome.

The integrity of the periplasmic domain of the VirA sensor kinase is critical for optimal coordination of the virulence signal response in Agrobacterium tumefaciens

Structural insights into the molecular mechanisms of cauliflower mosaic virus transmission by its insect vector.

Application of a sensitive collection heuristic for very large protein families: evolutionary relationship between adipose triglyceride lipase (ATGL) and classic mammalian lipases

Arabidopsis At5g39790 encodes a chloroplast-localized, carbohydrate-binding, coiled-coil domain-containing putative scaffold protein.

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