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The structure of haplotype blocks in the human genome

Science

May 25, 2002

Stacey B GabrielDavid Altshuler

Abstract

Haplotype-based methods offer a powerful approach to disease gene mapping, based on the association between causal mutations and the ancestral haplotypes on which they arose. As part of The SNP Consortium Allele Frequency Projects, we characterized haplotype patterns across 51 autosomal...read more

Mentioned in this Paper

In Silico
African Continental Ancestry Group
Recombination, Genetic
Genetic Association Studies
Genome Mapping
European Continental Ancestry Group
African American
Korean Race
Linkage Disequilibrium
Alleles
1
1210
1
4
Paper Details
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The structure of haplotype blocks in the human genome

Science

May 25, 2002

Stacey B GabrielDavid Altshuler

PMID: 12029063

DOI: 10.1126/science.1069424

Abstract

Haplotype-based methods offer a powerful approach to disease gene mapping, based on the association between causal mutations and the ancestral haplotypes on which they arose. As part of The SNP Consortium Allele Frequency Projects, we characterized haplotype patterns across 51 autosomal...read more

Mentioned in this Paper

In Silico
African Continental Ancestry Group
Recombination, Genetic
Genetic Association Studies
Genome Mapping
European Continental Ancestry Group
African American
Korean Race
Linkage Disequilibrium
Alleles
1
1210
1
4

Similar Papers Found In These Feeds

The National Human Genome Research Institute (NHGRI)

The National Human Genome Research Institute (NHGRI) supports research focusing on genomics related human health and disease. To stay updated on research published by NHGRI follow this feed.

General Biology Journal eTOCs

Discover the latest general biology research in this collection of the top biology journals.

Related Papers

Bioinformatics

Haploview: analysis and visualization of LD and haplotype maps

BioinformaticsAugust 7, 2004
J C BarrettM J Daly
Nature Genetics

High-resolution haplotype structure in the human genome

Nature GeneticsOctober 5, 2001
M J DalyE S Lander
Paper Details
References
  • References
  • Citations3154
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations3154
12345...
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