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The structure of haplotype blocks in the human genome

Science

Jun 21, 2002

Stacey Bolk GabrielDavid M Altshuler

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Abstract

Haplotype-based methods offer a powerful approach to disease gene mapping, based on the association between causal mutations and the ancestral haplotypes on which they arose. As part of The SNP Consortium Allele Frequency Projects, we characterized haplotype patterns across 51 autosomal...read more

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In Silico
Single Nucleotide Polymorphism
Korean Race
African Continental Ancestry Group
Linkage Disequilibrium
Recombination, Genetic
Genetic Association Studies
Computational Molecular Biology
Genome Mapping
European Continental Ancestry Group
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1164
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4
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The structure of haplotype blocks in the human genome

Science

Jun 21, 2002

Stacey Bolk GabrielDavid M Altshuler

PMID: 12029063

DOI: 10.1126/science.1069424

Abstract

Haplotype-based methods offer a powerful approach to disease gene mapping, based on the association between causal mutations and the ancestral haplotypes on which they arose. As part of The SNP Consortium Allele Frequency Projects, we characterized haplotype patterns across 51 autosomal...read more

Mentioned in this Paper

In Silico
Single Nucleotide Polymorphism
Korean Race
African Continental Ancestry Group
Linkage Disequilibrium
1
1164
1
4
Paper Details
References
  • References
  • Citations2958
  • References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations2958
12345...

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