PMID: 5257012Mar 1, 1969Paper

The structure of mouse-Elberfeld virus: a model

Proceedings of the National Academy of Sciences of the United States of America
R R RueckertC M Stoltzfus

Abstract

It is proposed that the capsid structure of mouse-Elberfeld (ME) virus, a small icosahedral ribonucleic acid containing picornavirus, is determined by 60 identical protein subunits; each of the latter is composed of several non-identical polypeptide chains. Icosahedral symmetry in a 60-subunit shell allows three types of specific intersubunit bonding contacts which establish its axes of two-, three-, and fivefold symmetry, respectively. Of these three bonding types, two are sufficient to specify a complete shell. We interpret the possible identity of some discrete supramolecular structures involved in the biosynthesis of poliovirus and in the degradation of ME virus in the context of stepwise formation or disruption of two different types of specific intersubunit bonding contacts.

References

Aug 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·D F SummersJ E Darnell
Sep 23, 1967·Nature·A T Burness, D S Walter
Jul 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·J J Holland, E D Kiehn
Jun 1, 1968·Virology·B A PhillipsJ V Maizel
Sep 7, 1967·Biochemical and Biophysical Research Communications·A L ShapiroJ V Maizel
Dec 17, 1965·Science·O Smithies
Jun 1, 1966·Journal of Molecular Biology·R R Rueckert, P H Duesberg
Mar 10, 1956·Nature·F H CRICK, J D WATSON
Jun 20, 1959·Nature·J T FINCH, A KLUG
Dec 31, 1962·Biochimica Et Biophysica Acta·Y WATANABEY HINUMA
Feb 1, 1964·Proceedings of the National Academy of Sciences of the United States of America·M D SCHARFFL LEVINTOW
Mar 1, 1964·Biochemistry·D A YPHANTIS

❮ Previous
Next ❯

Citations

Jan 1, 1973·Archiv für die gesamte Virusforschung·D Vanden Berghe, A Boeyé
Jan 1, 1974·Archiv für die gesamte Virusforschung·G F Vande Woude, R Ascione
Mar 1, 1970·Virology·D J O'CallaghanJ S Colter
Dec 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·B E ButterworthR R Rueckert
May 28, 1971·Journal of Molecular Biology·A K Dunker, R R Rueckert
Sep 5, 1972·Biochemical and Biophysical Research Communications·G F Vande WoudeH L Bachrach
Jul 1, 1990·Journal of Structural Biology·D G Scraba
Oct 23, 1970·Biochemical and Biophysical Research Communications·B D KorantS Halperen
Dec 1, 1971·Virology·G J Wu, G Bruening
May 1, 1971·Virology·K C MedappaR R Rueckert
Oct 1, 1973·Virology·B D Korant, J T Stasny
Jun 4, 1974·Biochemical and Biophysical Research Communications·S BernardJ Laporte
Jan 20, 1975·Biochemical and Biophysical Research Communications·J F DelagneauG Lenoir
Aug 1, 1972·Journal of Virology·Y GhendonA Mikhejeva
Mar 1, 1977·Journal of Virology·C W Bond, H E Swim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
B E ButterworthR R Rueckert
Journal of Molecular Biology
M F JacobsonD Baltimore
Biochemical and Biophysical Research Communications
B D KorantS Halperen
© 2021 Meta ULC. All rights reserved