PMID: 7335495Dec 21, 1981Paper

The structure of two subgenomic RNAs from human influenza virus A/PR/8/34

Nucleic Acids Research
G WinterG Ratti

Abstract

The nucleotide sequences of two subgenomic RNA segments from influenza virus A/PR/8/34 have been determined by cloning viral cDNA into the vector M13mp7. Sequence analysis was facilitated by a re-cloning strategy which takes advantage of both wild-type and amber derivatives of the M13 vector. The RNA species (444 and 480 nucleotides) contain the 5' and 3' termini of segment 1 and therefore derive by simple internal deletions of this segment. However, these species are not exact copies of the terminal regions of the progenitor segment but contain a few base changes. These differences suggest that after these RNAs have arisen, their sequences can drift, presumably reflecting a lower selective pressure than on the standard RNA segments.

References

Apr 1, 1979·Nucleic Acids Research·M J SleighG G Brownlee
Jul 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·A R Davis, D P Nayak
Sep 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·J MessingP Hans Hopschneider
Dec 1, 1977·Virology·A J HayJ J Skehel
Sep 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·D McGeochC Newton
Jan 24, 1981·Nucleic Acids Research·J MessingP H Seeburg
Oct 25, 1980·Journal of Molecular Biology·F SangerB A Roe
Jan 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·A R DavisD P Nayak
Apr 24, 1981·Nucleic Acids Research·B A Moss, G G Brownlee

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Citations

Dec 4, 2009·The Journal of General Virology·Edward C HutchinsonPaul Digard
Dec 15, 1984·Journal of Molecular Biology·K O'HareG M Rubin
Dec 25, 1982·Journal of Molecular Biology·F SangerG B Petersen
May 22, 2020·PLoS Pathogens·Fadi G Alnaji, Christopher B Brooke

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