The structures and properties of proton- and alkali-bound cysteine dimers

Physical Chemistry Chemical Physics : PCCP
Christian IeritanoW Scott Hopkins

Abstract

The proton-, lithium-, and sodium-bound cysteine dimers have been investigated in a joint computational and experimental infrared multiple photon dissociation (IRMPD) study. IRMPD spectra in the 1000-2000 cm(-1) region show that protonation is localized on an amine group, and that intermolecular hydrogen bonding occurs between the protonated amine and the carbonyl oxygen of the neutral Cys moiety. Alkali-bound dimers adopt structures reminiscent of those observed for the monomeric Cys·Li(+) and Cys·Na(+) species. Calculations of the heavier Cys2·M(+) (M = K, Rb or Cs) species suggest that these are significantly less strongly bound than the lighter (M = H, Li, or Na) dimers.

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May 3, 2014·The Journal of Physical Chemistry. a·Michael J LecoursW Scott Hopkins
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Citations

Dec 15, 2016·The Journal of Physical Chemistry Letters·Michael J LecoursW Scott Hopkins
Dec 9, 2016·Physical Chemistry Chemical Physics : PCCP·Weiqiang FuW Scott Hopkins
May 31, 2018·Physical Chemistry Chemical Physics : PCCP·Sven HeilesEvan R Williams
Oct 12, 2018·Physical Chemistry Chemical Physics : PCCP·Christian IeritanoW Scott Hopkins

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