The study protocol for the China Health Big Data (China Biobank) project

Quantitative Imaging in Medicine and Surgery
Yan WuX Cheng

Abstract

Osteoporosis, obesity, and fatty liver are increasingly common chronic diseases that seriously threaten people's health. Low-dose chest computed tomography (LDCT) scan is frequently used for lung cancer screening in health screenings and checkups. Quantitative computed tomography (QCT) enables the accurate measurement of volumetric bone mineral density (vBMD), liver fat content, and abdominal fat area using the existing LDCT data without extra radiation. We initiated a new project, the China Health Big Data (China Biobank), which combines the LDCT scan images from lung cancer screening of participants in health checkup with QCT to investigate the added value of QCT to LDCT, in order to establish the normative reference database and diagnosis criteria for the three aforementioned conditions. The China Biobank project is a prospective nationwide multicenter cohort study that will combine QCT technology with LDCT scans to measure bone mineral density (BMD), intra-abdominal fat distribution, and liver fat content of the generally healthy checkup participants. Mindways QCT calibration phantom (Mindways Software Inc., Austin, TX, USA) and analysis software QCT PRO v6.0 will be used for all centers. Before data collection begins, the ...Continue Reading

Citations

Oct 22, 2020·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Luping ZhangAlfred Otto Mueck
Nov 5, 2020·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Xiaoguang ChengUNKNOWN China Health Big Data (China Biobank) project investigators
Dec 2, 2020·Metabolism: Clinical and Experimental·Qiang ZengUNKNOWN China Health Big Data (China Biobank) project investigators
Feb 19, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·John T Schousboe, Kristine E Ensrud
Mar 23, 2021·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Yingwei ZhaoXiaoguang Cheng

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