The study protocol of a blinded randomised-controlled cross-over trial of lavender oil as a treatment of behavioural symptoms in dementia.

BMC Geriatrics
Eva S van der PloegDaniel W O'Connor

Abstract

The agitated behaviours that accompany dementia (e.g. pacing, aggression, calling out) are stressful to both nursing home residents and their carers and are difficult to treat. Increasingly more attention is being paid to alternative interventions that are associated with fewer risks than pharmacology. Lavandula angustifolia (lavender) has been thought, for centuries, to have soothing properties, but the existing evidence is limited and shows mixed results. The aim of the current study is to test the effectiveness of topically applied pure lavender oil in reducing actual counts of challenging behaviours in nursing home residents. We will use a blinded repeated measures design with random cross-over between lavender oil and placebo oil. Persons with moderate to severe dementia and associated behavioural problems living in aged care facilities will be included in the study. Consented, willing participants will be assigned in random order to lavender or placebo blocks for one week then switched to the other condition for the following week. In each week the oils will be applied on three days with at least a two-day wash out period between conditions. Trained observers will note presence of target behaviours and predominant type of...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Nov 1, 1991·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·G BuchbauerC Plank
Oct 1, 1986·Journal of the American Geriatrics Society·J Cohen-Mansfield
Jun 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·C P HughesR L Martin
Apr 1, 1995·Neurochemical Research·E ElisabetskyD O Souza
Jun 1, 1993·Journal of Pharmaceutical Sciences·G BuchbauerH Dietrich
Jan 1, 1996·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·M P LawtonJ Klapper
May 1, 1997·The British Journal of Clinical Psychology·D J BrookerM Payne
Mar 9, 1999·The International Journal of Neuroscience·M A DiegoM Galamaga
Oct 19, 2001·International Journal of Geriatric Psychiatry·J SmallwoodC Copland
Dec 12, 2001·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·J Cohen-Mansfield
Jan 22, 2002·International Journal of Geriatric Psychiatry·Janet OpieDaniel W O'Connor
May 8, 2002·International Journal of Geriatric Psychiatry·Clive HolmesHenry Rosenvinge
Jun 27, 2002·American Journal of Alzheimer's Disease and Other Dementias·Suzanne G Gray, Alicia Ann Clair
Jul 16, 2004·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Lynn A SnowJason Brandt
Sep 28, 2005·International Psychogeriatrics·Susannah J RunciDaniel W O'Connor
Mar 1, 2006·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Lon S SchneiderPhilip S Insel
Jun 1, 2006·International Psychogeriatrics·Susannah J RunciDaniel W O'Connor
Feb 13, 2007·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Kathryn GarlandDaniel W O'Connor
Sep 26, 2008·International Psychogeriatrics·Daniel W O'ConnorMadeleine King

❮ Previous
Next ❯

Citations

Feb 3, 2016·Nursing and Midwifery Studies·Sayyed Hossein HashemiMohammad Aghajani
Dec 23, 2015·BioMed Research International·Alexandra Martini de OliveiraOrestes V Forlenza
Jul 28, 2015·Nursing in Critical Care·Ezgi KaradagErcan Bakir
May 14, 2016·Soins. Gérontologie·Corinne BilienNathalie Baptiste
Oct 18, 2014·Clinical Rehabilitation·Juan Rodríguez-MansillaElisa María Garrido-Ardila
Feb 27, 2014·The Cochrane Database of Systematic Reviews·Lene Thorgrimsen ForresterKarla Soares-Weiser
Aug 20, 2020·The Cochrane Database of Systematic Reviews·Emily L BallJenny McCleery
Jun 20, 2020·Journal of Geriatric Psychiatry and Neurology·Cemile Kütmeç Yilmaz, Güler Duru Aşiret
Nov 9, 2021·Geriatrics & Gerontology International·Hyegyeong ChaKyum-Yil Kwon

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation

Software Mentioned

Excel

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.