PMID: 4819905Feb 1, 1974

The 'subcortical dementia' of progressive supranuclear palsy

Journal of Neurology, Neurosurgery, and Psychiatry
M L AlbertA L Willis

Abstract

Progressive supranuclear palsy (Steele et al.) has a characteristic pattern of dementia: (1) forgetfulness, (2) slowing of thought processes, (3) emotional or personality changes (apathy or depression with occasional outbursts of irritability), and (4) impaired ability to manipulate acquired knowledge. In many neurological disease states associated with subcortical pathology a similar pattern of dementia exists. The neurobehavioural changes of progressive supranuclear palsy thus typify a clinical pattern which may be referred to as subcortical dementia. The subcortical dementias have a striking clinical resemblance to the dementia which occurs after bifrontal lobe disease. However, the subcortical dementias can be clearly distinguished clinically from cortical dementias, other than frontal dementias. We propose as a tentative hypothesis that there may be common pathophysiological mechanisms underlying the subcortical dementias-in particular, disturbances of timing and activation. There are immediate practical implications of this hypothesis: drugs which have an effect on subcortical timing and activating mechanisms may be useful in the treatment of subcortical dementias.

References

Aug 29, 1970·Lancet·I Dehaene, M Bogaerts
Jan 1, 1968·Brain : a Journal of Neurology·D S Bell
Aug 1, 1971·Journal of Psychiatric Research·W J Nauta
Apr 1, 1968·Neurology·N J DavidJ L Smith
Apr 1, 1969·Archives of Neurology·H Blumenthal, C Miller
Jan 1, 1969·Brain : a Journal of Neurology·S BehrmanW B Matthews
Sep 1, 1966·Brain : a Journal of Neurology·M Pollock, R W Hornabrook
May 1, 1954·Journal of Neurology, Neurosurgery, and Psychiatry·M WILLIAMS, J PENNYBACKER
Oct 1, 1958·Anaesthesia·D A B HOPKIN, D BROWN

Citations

Dec 25, 2013·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Lealani Mae Y AcostaKenneth M Heilman
Nov 1, 1992·Journal of Clinical Psychology·T Swirsky-SacchettiC F Gonzalez
Aug 6, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·L DefebvreA Destée
Mar 26, 2003·American Journal of Physical Anthropology·P Lieberman
Sep 1, 1983·Annals of Neurology·R MayeuxF Benson
Aug 1, 1996·Annals of Neurology·M B Feany, Dennis W Dickson
Dec 19, 2001·Movement Disorders : Official Journal of the Movement Disorder Society·J KulisevskyJ L Cummings
Jan 1, 1992·Acta Neuropathologica·H BraakJ Bohl
Sep 1, 1991·Journal of Neurology·S SasakiC Toyoda
Jan 1, 1995·Acta Neuropathologica·I R Mackenzie, L P Hudson
Jan 1, 1987·Neuroradiology·H SaitohY Shinohara
Sep 1, 1990·Neuropsychology Review·S A RaskinJ Tweedy
Sep 1, 1991·Neuroscience and Behavioral Physiology·I V DamulinO A Goncharov
Jan 1, 1997·Journal of Neural Transmission·G K WenningIrene Litvan
Oct 1, 1996·European Journal of Nuclear Medicine·W C ShyuW L Tsao
Jan 1, 1991·European Archives of Psychiatry and Clinical Neuroscience·A BoguckiR Szymańska
Oct 1, 1980·Italian Journal of Neurological Sciences·A BrusaO Bugiani
Jan 1, 1993·Italian Journal of Neurological Sciences·A DanieleC Gainotti
Nov 1, 1994·Italian Journal of Neurological Sciences·Paola SoliveriF Girotti
Apr 1, 1997·Journal of Neurology·L HokkanenM Iivanainen
Sep 3, 2011·Journal of Molecular Neuroscience : MN·Andrew KerteszSarah Jesso
Jul 1, 1987·British Journal of Hospital Medicine·M Rossor
Jun 1, 1987·Biological Psychiatry·M Webb, P T Trzepacz
Jun 1, 1992·Biological Psychiatry·U D McCannG Belenky
Oct 1, 1986·Electroencephalography and Clinical Neurophysiology·C J Fowler, M J Harrison
Sep 1, 1988·Journal of the Neurological Sciences·H HeiskalaM Haltia
Jun 1, 1988·Journal of the Neurological Sciences·A Jennekens-SchinkelE A van der Velde
Nov 1, 1990·Journal of the Neurological Sciences·A Jennekens-SchinkelE A van der Velde
Apr 1, 1993·Journal of the Neurological Sciences·M Prosiegel, C Michael
Sep 1, 1995·Journal of the Neurological Sciences·M J Pijpers-KooimanA Jennekens-Schinkel
Mar 1, 1995·General Hospital Psychiatry·H F Chiu
Jan 1, 1991·Brain Research. Brain Research Reviews·R M Ridley, H F Baker
Aug 1, 1994·Brain Research. Brain Research Reviews·C H Vanderwolf, D P Cain
Aug 1, 1994·Brain Research. Brain Research Reviews·T StecklerA Sahgal
Aug 1, 1991·Psychiatry Research·R S MarinS Firinciogullari
Jan 1, 1987·Clinical Neurology and Neurosurgery·M M DerixB W Verbeeten
Jan 1, 1989·Clinical Neurology and Neurosurgery·A LeeC M Chang
May 1, 1988·Neuroscience·R G Brown, C D Marsden
Jun 1, 1987·Brain Research Bulletin·E Garcia-RillD J Woodward
Jan 1, 1990·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·L R SapinJ L Sherman
Sep 7, 2005·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Juan Carlos Arango-LasprillaFrancisco Lopera
Nov 5, 2003·Experimental Neurology·Norman L Foster
Aug 14, 1998·Journal of the Neurological Sciences·F Boller, M M Forbes
Oct 31, 2001·Neuropsychologia·M LamarD J Libon
Jun 9, 1999·Journal of Affective Disorders·S SimpsonA Burns
Mar 17, 1999·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J D Kropotov, S C Etlinger
Oct 9, 1999·Progress in Neurobiology·E BrouilletP Hantraye
Sep 7, 2000·Brain Research Bulletin·K AbeT Yanagihara
Sep 5, 2001·Neurologic Clinics·G Glosser
Nov 1, 2003·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·T GiovannettiD J Libon
Jul 2, 2008·Parkinsonism & Related Disorders·A WallinA-K Granérus
Oct 9, 2002·Comptes rendus biologies·Jean-Jacques Hauw, C Duyckaerts
Feb 1, 1988·Psychological Medicine·S Hart
May 1, 1986·Psychological Medicine·D Rogers
May 1, 1990·Psychological Medicine·H E NelsonT R Barnes
Nov 1, 1991·Psychological Medicine·J L BoydE G Spokes
Nov 1, 1995·Journal of the International Neuropsychological Society : JINS·K R HanesC Pantelis
Jan 2, 2001·Neuropathology : Official Journal of the Japanese Society of Neuropathology·K UrasakiI Nakano
Apr 22, 1999·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·K DujardinP Hautecoeur
Apr 22, 1999·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·R PahwaW Koller
Nov 1, 1984·Journal of Clinical Neuropsychology·J BrandtM Folstein
Oct 1, 1986·Journal of Clinical and Experimental Neuropsychology·S M Rao
Apr 1, 1987·Journal of Clinical and Experimental Neuropsychology·D T StussG Laflèche
Aug 1, 1989·Journal of Clinical and Experimental Neuropsychology·S M RaoG J Leo
Oct 1, 1989·Journal of Clinical and Experimental Neuropsychology·W Milberg, M S Albert
Oct 1, 1989·Journal of Clinical and Experimental Neuropsychology·S M RaoP St Aubin-Faubert
Oct 1, 1990·Journal of Clinical and Experimental Neuropsychology·P MassmanDavid P Salmon
Nov 1, 1991·Journal of Clinical and Experimental Neuropsychology·M F Mendez, M Ashla-Mendez
May 1, 1995·Journal of Clinical and Experimental Neuropsychology·P R van der Hurk, John R Hodges
Feb 1, 1996·Journal of Clinical and Experimental Neuropsychology·M D Lucas, B R Sonnenberg
Apr 3, 1998·Journal of Clinical and Experimental Neuropsychology·J Vincent FiloteoJ W Roberts
Jun 1, 1997·Journal of Clinical and Experimental Neuropsychology·D A WhiteI Grant
Apr 1, 1994·Experimental Aging Research·D R Royall
Aug 12, 2005·Neurocase·Paola SoliveriFloriano Girotti
Mar 17, 2007·Journal of Clinical and Experimental Neuropsychology·Jose M LafosseChristopher M Filley
Dec 13, 2005·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Vanessa S ZizakDavid P Salmon
Mar 12, 2008·The Neurologist·Raphael M Bonelli, J L Cummings
Sep 18, 2008·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Andrew Kertesz
Nov 11, 2008·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Rieko SakamotoMasaru Mimura
Jun 11, 2009·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Rieko SakamotoMasaru Mimura
Jan 1, 1982·Folia Psychiatrica Et Neurologica Japonica·Y Nakamura
Nov 1, 1994·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·D PozziS Starkstein
Oct 8, 2004·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A Jimenez-EscrigL Orensanz
Jun 27, 2006·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·P VisaniThomas Benke
Jun 3, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C C ChangW L Liu
Sep 1, 1996·Alcoholism, Clinical and Experimental Research·S N MattsonK L Jones
Nov 1, 1976·Acta Neurologica Scandinavica·R J Marttila, U K Rinne
Jan 1, 1992·Acta Neurologica Scandinavica. Supplementum·E S Tolosa, R Alvarez
Apr 1, 1997·Acta Neurologica Scandinavica·M E ZöllerL Bäckman
Apr 1, 1991·Acta Psychiatrica Scandinavica·E PoutiainenM Iivanainen
May 1, 1992·Acta Psychiatrica Scandinavica·R MorrissM Folstein
Nov 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·R H MindhamC G Clough
Dec 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·Y de SmetY Agid
Apr 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·D LaplaneB Dubois
Dec 1, 1985·Journal of Neurology, Neurosurgery, and Psychiatry·E R MaherA J Lees
Dec 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·A Jennekens-Schinkel, E A Sanders
Oct 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·R P Hart, J A Kwentus
Sep 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·David NearyH J Testa
Jan 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·D R WeinbergerR F Zec
Mar 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·David NearyP Goulding
Jun 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·R G MorrisT W Robbins
Dec 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·John R HodgesN Butters
Mar 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·P S SachdevP Rodriguez
May 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·J BrownM Rossor
Nov 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·A Rosser, John R Hodges
Dec 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·M Rossor
May 12, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·A M PlohmannJ Lechner-Scott
Aug 14, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·M AsahinaT Hattori
Feb 1, 1988·Postgraduate Medical Journal·P Tyrrell, M Rossor
Mar 29, 2007·Dementia and Geriatric Cognitive Disorders·Inga LiepeltDaniela Berg
Sep 14, 2012·Therapeutic Advances in Neurological Disorders·Christopher M Filley
Nov 30, 1999·Applied Neuropsychology·K K Zakzanis, M Freedman
Feb 27, 2010·Journal of Psychiatry & Neuroscience : JPN·Chiung-Chih ChangChing Chen
Dec 26, 2013·Clinical Interventions in Aging·Simona SpaccaventoAnna Loverre
Jun 1, 1986·The Australian and New Zealand Journal of Psychiatry·F A Whitlock
Mar 1, 1993·The Australian and New Zealand Journal of Psychiatry·G J KernuttG D Burrows
Jul 1, 1990·Journal of Neurology·B CensoriL Provinciali
Jun 1, 1990·Molecular and Chemical Neuropathology·D EdwinH Moser
Jan 1, 1981·Neuropsychologia·D KimuraG Burkhart
Apr 10, 2004·High Altitude Medicine & Biology·Chie UsuiHeii Arai
May 26, 2001·Clinics in Geriatric Medicine·Dennis W Dickson
May 26, 2001·Clinics in Geriatric Medicine·David S Knopman
May 1, 1981·The British Journal of Clinical Practice·J Wagstaff, A C Young
Aug 1, 1990·The International Journal of Neuroscience·A M Horton, E Siegel
Jun 1, 1989·Mayo Clinic Proceedings·Ronald C Petersen, E Kokmen
Nov 1, 1995·Psychosomatics·M A MenzaL I Golbe
Feb 20, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Michael J HoganLawrence J Whalley
Aug 18, 2009·Revue neurologique·C Ardouingroupe évaluation comportementale de la maladie de Parkinson
Sep 8, 2009·Journal of the Neurological Sciences·Andrew Kertesz, Paul McMonagle
Oct 9, 2003·Mayo Clinic Proceedings·David S KnopmanRonald C Petersen
May 18, 2000·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·P FaglioniE Merelli
Jul 1, 1989·Geriatric Nursing·A KedasW E Lux
Jul 31, 2007·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Jeffrey M Rogers, Peter K Panegyres
Apr 5, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Keith A JosephsClifford R Jack
Mar 31, 2011·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Yusuke YatabeManabu Ikeda
Mar 18, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Emma C SchofieldGlenda M Halliday
Sep 17, 2014·Journal of Neuropsychology·Young-Eun C LeeJacqueline F I Anderson
Mar 9, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Laura Silveira-MoriyamaAndrew J Lees
Dec 1, 1988·Brain and Cognition·D T StussS Larochelle
Jun 1, 1988·Brain and Cognition·E Granholm, N Butters
Oct 1, 1996·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·W G ReidP M Williamson
Sep 1, 1982·Comprehensive Psychiatry·P V Rabins
Jan 1, 1982·Comprehensive Psychiatry·J H Dowson
Jul 1, 1978·Comprehensive Psychiatry·Z J Lipowski
Jun 1, 1982·Journal of the American Geriatrics Society·E C Shuttleworth
Sep 1, 1986·Journal of the American Geriatrics Society·L S Schneider, H C Chui
Jul 1, 1988·Acta Neurologica Scandinavica·E PoutiainenJ Lähdevirta
Jun 20, 2006·Journal of the Neurological Sciences·Elka StefanovaVladimir S Kostic
Jun 20, 2006·Journal of the Neurological Sciences·Jim GrigsbyPaul J Hagerman
Dec 27, 2005·General Hospital Psychiatry·Akira Kugaya, Catherine Chiles
Nov 18, 2005·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Marjorie A MurphyStewart A Factor
Feb 1, 1996·Neurologic Clinics·T A Sandson, B H Price
Jan 27, 1998·The Psychiatric Clinics of North America·C R Savage
Sep 1, 1992·Neurophysiologie clinique = Clinical neurophysiology·J C PinR Gil
Apr 6, 2004·Clinics in Geriatric Medicine·David S Geldmacher
Feb 11, 2015·Journal of Neurology·Christopher KobyleckiAlexander Gerhard
Jan 22, 1998·Journal of the American Geriatrics Society·D R Royall, M Polk
May 16, 2014·Applied Neuropsychology. Adult·Robert J Sbordone
Jul 18, 2008·Handbook of Clinical Neurology·Shaheda N Azher, Joseph Jankovic
May 16, 2000·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S V SuarezB Dubois
Sep 10, 2013·Journal of Neurology, Neurosurgery, and Psychiatry·Carlo ColosimoAlfredo Berardelli
Feb 4, 2003·Arquivos de neuro-psiquiatria·Paulo Eduardo Mestrinelli Carrilho, Egberto Reis Barbosa
Oct 1, 1996·Journal of Geriatric Psychiatry and Neurology·A WallinM Sjögren
Jan 1, 1988·Journal of Geriatric Psychiatry and Neurology·J L Cummings
Jan 1, 1990·Journal of Geriatric Psychiatry and Neurology·D J LibonH B Coslet
Dec 6, 2000·Journal of Psychopharmacology·J R Berger, G Arendt
Apr 1, 1989·Journal of Geriatric Psychiatry and Neurology·L S SchneiderH C Chui
Aug 30, 2000·Multiple Sclerosis : Clinical and Laboratory Research·R H LazeronF Barkhof
Jan 21, 2016·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Roxane PeresEric Jouvent
Oct 1, 1995·Journal of Geriatric Psychiatry and Neurology·D J Knesper
May 26, 2004·Journal of Geriatric Psychiatry and Neurology·Kenichi MeguroMasatoshi Itoh
Dec 11, 1999·Journal of Geriatric Psychiatry and Neurology·R G RobinsonR Jorge
Jan 3, 2018·Brain : a Journal of Neurology·Thomas E CopeJames B Rowe
Dec 5, 2017·Journal of the International Neuropsychological Society : JINS·Mark W BondiDavid P Salmon
Dec 20, 2017·Journal of Alzheimer's Disease : JAD·James R BurrellJohn R Hodges
Nov 1, 1984·Stroke; a Journal of Cerebral Circulation·Y KitagawaR L Rogers
Mar 1, 1987·Stroke; a Journal of Cerebral Circulation·I MeissnerS D Stein
Jan 1, 1991·Annals of the New York Academy of Sciences·E J Metter
May 16, 2007·Journal of Neurology·Pasquale Calabrese, Iris Katharina Penner
Aug 21, 1993·BMJ : British Medical Journal·S Bulusu
Aug 21, 1993·BMJ : British Medical Journal·J C Pickup, M A Crook
Aug 21, 1993·BMJ : British Medical Journal·R JonesC Tait
Jan 1, 1991·Acta Psychiatrica Scandinavica. Supplementum·H Lauter, S Dame
Jan 1, 1978·Folia Psychiatrica Et Neurologica Japonica·M YamadaK Nakamura
Aug 1, 1995·Neuropathology and Applied Neurobiology·T HaniharaS Yagashita
Jul 9, 2010·Current Opinion in Neurology·Dennis W DicksonKeith A Josephs
Oct 4, 2005·Movement Disorders : Official Journal of the Movement Disorder Society·David MillarDavid J Burn
Apr 1, 1992·The British Journal of Psychiatry : the Journal of Mental Science·C PantelisH E Nelson
May 1, 1989·The British Journal of Psychiatry : the Journal of Mental Science·W R Gibb
Feb 1, 1989·The British Journal of Psychiatry : the Journal of Mental Science·E M Joyce, R Levy
Dec 1, 1986·The British Journal of Psychiatry : the Journal of Mental Science·J L Cummings
Jan 1, 1981·The British Journal of Psychiatry : the Journal of Mental Science·M R Trimble, J L Cummings
Aug 2, 2002·Current Opinion in Neurology·Andrew Feigin, Dennis Zgaljardic
Aug 29, 2012·Movement Disorders : Official Journal of the Movement Disorder Society·David J Burn
Dec 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·D M Girling, G E Berrios
Apr 19, 1986·British Medical Journal·J B Foster
Mar 1, 1985·Acta Neurologica Scandinavica·M O Kristensen
Nov 1, 1986·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·M Freedman, M Oscar-Berman
Jun 1, 1985·Annals of Neurology·R P HartR Frazier
Feb 1, 1984·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·A J Gomori, A A Sima
Jan 1, 1983·Acta Neuropathologica·F TagliaviniA Lechi
Jul 3, 1993·BMJ : British Medical Journal·F J Dunne
Dec 1, 1996·Arquivos de neuro-psiquiatria·L de A Pamplona, J P De Mattos
Aug 12, 2016·Journal of Neurophysiology·Christopher M Filley, R Douglas Fields
Oct 1, 2016·Dementia & Neuropsychologia·Antonio Lucio TeixeiraEdward C Lauterbach
Jul 20, 2019·Journal of Neurology·Katie A PetersonJames B Rowe
Mar 1, 1982·The International Journal of Neuroscience·G W HyndG J Maletta
Sep 1, 1993·The British Journal of Psychiatry : the Journal of Mental Science·J T O'BrienS A Checkley
Dec 1, 1989·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·E McCrank, K Rabheru
Jan 26, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·V PharrM Stark
May 4, 2004·CNS Spectrums·Thomas Benke, Elfriede Karner
Oct 24, 2006·Arquivos de neuro-psiquiatria·Carlos G AbelRoberto E P Sica
Nov 7, 2019·Frontiers in Neurology·Ali ShoeibiIrene Litvan
Nov 1, 1986·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·H TeräväinenD B Calne
Apr 1, 1985·Annals of Neurology·P H DavisD R McLachlan
Dec 1, 1988·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·E K Koranyi
Jun 12, 2001·Journal of Neuropathology and Experimental Neurology·K Ishizawa, Dennis W Dickson
May 1, 1985·Psychological Medicine·B Mahendra
Aug 21, 1993·BMJ : British Medical Journal·T HughesC A Biggins
Feb 2, 2002·The British Journal of Psychiatry : the Journal of Mental Science·Mark A TurnerMichael D Kopelman
Oct 31, 2017·Movement Disorders : Official Journal of the Movement Disorder Society·Shunsuke KogaDennis W Dickson
Nov 1, 1985·The British Journal of Psychiatry : the Journal of Mental Science·J L Waddell, C J Gillard
Jun 1, 1986·Developmental Medicine and Child Neurology·R P HartR T Leshner
Jul 1, 1985·Postgraduate Medicine·G W Paulson
Aug 28, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Eleonora Del PreteRoberto Ceravolo
Nov 10, 1998·Journal of Psychopharmacology·J D Amsterdam

Related Concepts

Emotional Disturbances
Brain
Brain Pathology
Overinclusion
Senile Paranoid Dementia
Dihydroxyphenylalanine Hydrochloride, (2:1)
Memory Loss
Ophthalmoparesis
Fazio-Londe Syndrome
Narcissistic Personality Disorder

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.