The successful treatment of symptomatic, refractory hepatic hydrothorax with transjugular intrahepatic portosystemic shunt

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
F D GordonC Trey

Abstract

Hepatic hydrothorax is a rare complication of portal hypertension. Conservative therapy may be successful but refractory hepatic hydrothorax is not uncommon. Management of refractory hydrothorax is usually ineffective and can result in a worsened clinical status. Transjugular intrahepatic portosystemic shunts (TIPS) lower portal pressure and have been used in the treatment of refractory ascites. The aim of this study was to determine the efficacy of TIPS in the treatment of symptomatic refractory hepatic hydrothorax. A TIPS was placed in 24 consecutive cirrhotic patients with symptomatic refractory hepatic hydrothorax. Five patients (20.8%) were Child's/Pugh class B and 19 (79.2%) were class C. All had undergone multiple thoracenteses and were hypoalbuminemic. Mean follow-up was 7.2 months (range, 0.25-49 months). Fourteen (58.3%) of 24 patients had complete relief of symptoms after shunt placement and did not require further thoracentesis. Five (20.8%) additional patients required fewer thoracenteses. Five (20.8%) patients developed worsening liver function and died within 45 days. In eight (66.7%) of 12 patients with > or = 60 days of follow-up, the serum albumin increased by a mean of 1.2 g/dL (range, 0.1-2.2 g/dL). The Chil...Continue Reading

Citations

Sep 2, 1998·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·M A JeffriesR J Fontana
May 13, 2008·General Thoracic and Cardiovascular Surgery·Takayuki IbiKazuo Shimizu
Sep 12, 2000·Current Gastroenterology Reports·A J Sanyal
Jan 18, 2003·Current Gastroenterology Reports·Timothy M McCashland
Aug 12, 2009·Hepatology International·Eric S Orman, Anna S F Lok
Sep 24, 1999·The American Journal of Medicine·K N LazaridisP S Kamath
Mar 29, 2000·The Annals of Thoracic Surgery·L D ConklinM J Reardon
May 23, 2003·Gastroenterology·Thomas D Boyer
Nov 29, 2002·Seminars in Roentgenology·Nilesh H Patel
May 8, 2001·Journal of Gastroenterology and Hepatology·A BhattacharyaY Chawla
Dec 1, 2005·Seminars in Interventional Radiology·Michael J Wallace, David C Madoff
Jan 15, 2000·Journal of Clinical Gastroenterology·J P OngZ M Younossi
Sep 1, 1999·Journal of Pediatric Gastroenterology and Nutrition·M B Heyman, J M LaBerge
May 24, 2000·The Journal of Trauma·D LudwigR V Maier
Dec 16, 1998·Australian and New Zealand Journal of Medicine·D B WilliamsW Selby
Apr 5, 2003·BMJ : British Medical Journal·Jakob BorchardtStephen Malnick
Sep 13, 2006·Gut·K P Moore, G P Aithal
Dec 22, 1999·Gut·M J Krowka
Mar 15, 2000·Gut·R JalanP C Hayes
May 13, 1999·Postgraduate Medical Journal·N H PatelR M Jindal
May 28, 2005·Digestive Diseases·Andreas Ochs
Sep 2, 2009·Drugs·Fedja A Rochling, Rowen K Zetterman
Oct 14, 2011·International Journal of Hepatology·Prabha SawantM Nasa
Jul 7, 2011·World Journal of Hepatology·Meir MizrahiOren Shibolet
May 21, 2011·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Taichiro GotoRyoichi Kato
Oct 23, 2012·American Journal of Therapeutics·Kiran BaikatiSury Anand
Aug 14, 2012·International Journal of Hepatology·Gilles Pomier-LayrarguesPierre Perreault
Dec 2, 2014·Clinics in Liver Disease·Kavish R PatidarArun J Sanyal
Apr 1, 2014·Clinics in Liver Disease·John Paul Norvell, James R Spivey
Aug 17, 2010·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Wei-Lun LiuPan-Chyr Yang
Oct 4, 2013·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Victor I MachicaoMichael B Fallon
Jul 14, 2000·Chest·J R Milanez de CamposF B Jatene
Feb 14, 2004·Journal of Vascular and Interventional Radiology : JVIR·Timothy W I ClarkS William Stavropoulos
Jun 28, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Harjit K Bhogal, Arun J Sanyal
Jul 10, 2004·Gastroentérologie Clinique Et Biologique·Sami AjmiHabib Essabbah
Apr 5, 2002·Journal of Vascular and Interventional Radiology : JVIR·E Brooke SpencerMichael D Darcy
Mar 15, 2000·Journal of Vascular and Interventional Radiology : JVIR·J J BorsaU P Schmiedl
Feb 7, 2002·Journal of Vascular and Interventional Radiology : JVIR·Dheeraj K RajanTimothy W I Clark
Jan 16, 2007·Best Practice & Research. Clinical Gastroenterology·Andrés Cárdenas, Vicente Arroyo
Jan 2, 2007·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·M SenzoloA K Burroughs
Mar 15, 2006·Gastroenterology Clinics of North America·William Sanchez, Jayant A Talwalkar

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